SCOPe 2.06: Domain d3jzca_: 3jzc A:

Lineage for d3jzca_ (3jzc A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Thyroid hormone receptor beta (TR-beta) [48530] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48531] (16 PDB entries)
   Uniprot P10828 202-460

8. Domain d3jzca_: 3jzc A: [178929]
   automated match to d1nq0a_
   complexed with 4hy

Details for d3jzca_

PDB Entry: 3jzc, 2.5 Å

PDB Description: Crystal Structure of TR-beta bound to the selective thyromimetic TRIAC

PDB Compounds: (A:) Thyroid hormone receptor beta

SCOPe Domain Sequences for d3jzca_:

Sequence, based on SEQRES records:

>d3jzca_ a.123.1.1 (A:) Thyroid hormone receptor beta (TR-beta) {Human (Homo sapiens) [TaxId: 9606]}
eelqksighkpeptdeeweliktvteahvatnaqgshwkqkrkflpedigqapivnapeg
gkvdleafshftkiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslraavry
dpesetltlngemavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavllmss
drpglacveriekyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachasrflh
mkvecptelfpplflevfe

Sequence, based on observed residues (ATOM records):

>d3jzca_ a.123.1.1 (A:) Thyroid hormone receptor beta (TR-beta) {Human (Homo sapiens) [TaxId: 9606]}
eelqksighkpeptdeeweliktvteahvatnaqgshwkqkrkflpedigqvdleafshf
tkiitpaitrvvdfakklpmfcelpcedqiillkgccmeimslraavrydpesetltlng
emavtrgqlkngglgvvsdaifdlgmslssfnlddtevallqavllmssdrpglacveri
ekyqdsfllafehyinyrkhhvthfwpkllmkvtdlrmigachasrflhmkvecptelfp
plflevfe

Timeline for d3jzca_:

• d3jzca_ first appeared in SCOPe 2.01
  
• d3jzca_ appears in SCOPe 2.05
  
• d3jzca_ appears in SCOPe 2.07
  
• d3jzca_ appears in the current release, SCOPe 2.08