SCOPe 2.04: Domain d3iwoa_: 3iwo A:

Lineage for d3iwoa_ (3iwo A:)

1. Root: SCOPe 2.04

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.3: beta-lactamase/transpeptidase-like [56600] (1 superfamily)
   contains a cluster of helices and an alpha+beta sandwich

4. Superfamily e.3.1: beta-lactamase/transpeptidase-like [56601] (4 families)

5. Family e.3.1.1: beta-Lactamase/D-ala carboxypeptidase [56602] (19 proteins)

6. Protein AMPC beta-Lactamase, class C [56618] (3 species)
   contains small alpha+beta subdomain inserted in the common fold

7. Species Escherichia coli, cephalosporinase [TaxId:562] [56621] (95 PDB entries)

8. Domain d3iwoa_: 3iwo A: [178653]
   automated match to d1c3ba_
   complexed with po4, suc; mutant

Details for d3iwoa_

PDB Entry: 3iwo, 1.9 Å

PDB Description: x-ray crystal structure of the extended-spectrum ampc y221g mutant beta-lactamase at 1.90 angstrom resolution

PDB Compounds: (A:) Beta-lactamase

SCOPe Domain Sequences for d3iwoa_:

Sequence, based on SEQRES records:

>d3iwoa_ e.3.1.1 (A:) AMPC beta-Lactamase, class C {Escherichia coli, cephalosporinase [TaxId: 562]}
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaggvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiingsdnkialaarpvkaitp
ptpavraswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq

Sequence, based on observed residues (ATOM records):

>d3iwoa_ e.3.1.1 (A:) AMPC beta-Lactamase, class C {Escherichia coli, cephalosporinase [TaxId: 562]}
apqqindivhrtitplieqqkipgmavaviyqgkpyyftwgyadiakkqpvtqqtlfelg
svsktftgvlggdaiargeiklsdpttkywpeltakqwngitllhlatytagglplqvpd
evksssdllrfyqnwqpawapgtqrlyanssiglfgalavkpsglsfeqamqtrvfqplk
lnhtwinvppaeeknyawgyregkavhvspgaldaeaggvkstiedmarwvqsnlkpldi
nektlqqgiqlaqsrywqtgdmyqglgwemldwpvnpdsiiialaarpvkaitpptpavr
aswvhktgatggfgsyvafipekelgivmlanknypnparvdaawqilnalq

Timeline for d3iwoa_:

• d3iwoa_ first appeared in SCOPe 2.01
  
• d3iwoa_ appears in SCOPe 2.03
  
• d3iwoa_ appears in SCOPe 2.05
  
• d3iwoa_ appears in the current release, SCOPe 2.08