SCOPe 2.02: Domain d3i0sb_: 3i0s B:

Lineage for d3i0sb_ (3i0s B:)

1. Root: SCOPe 2.02

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (6 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein automated matches [190211] (3 species)
   not a true protein

7. Species Hiv-1 m:b_hxb2r [TaxId:11706] [187165] (8 PDB entries)

8. Domain d3i0sb_: 3i0s B: [178008]
   automated match to d1c1cb_
   protein/DNA complex; protein/RNA complex; complexed with rt7

Details for d3i0sb_

PDB Entry: 3i0s, 2.7 Å

PDB Description: crystal structure of HIV reverse transcriptase in complex with inhibitor 7

PDB Compounds: (B:) p51 RT

SCOPe Domain Sequences for d3i0sb_:

Sequence, based on SEQRES records:

>d3i0sb_ e.8.1.2 (B:) automated matches {Hiv-1 m:b_hxb2r [TaxId: 11706]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpi
vlpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelela
enreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtnd
vkqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvk
lwyq

Sequence, based on observed residues (ATOM records):

>d3i0sb_ e.8.1.2 (B:) automated matches {Hiv-1 m:b_hxb2r [TaxId: 11706]}
ietvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaik
kkdstkwrklvdfrelnkrtqdfwevqlgiphpaglkkkksvtvldvgdayfsvpldedf
rkytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqym
ddlyvgsdleigqhrtkieelrqhllrwgltgyelhpdkwtvqpivlpekdswtvndiqk
lvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyy
dpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarhtndvkqlteavqkittesiviw
gktpkfklpiqketwetwwteywqatwipewefvntpplvklwyq

Timeline for d3i0sb_:

• d3i0sb_ first appeared in SCOPe 2.01
  
• d3i0sb_ appears in SCOPe 2.03
  
• d3i0sb_ appears in the current release, SCOPe 2.08