SCOPe 2.03: Domain d3fa6a_: 3fa6 A:

Lineage for d3fa6a_ (3fa6 A:)

1. Root: SCOPe 2.03

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.60: Lipocalins [50813] (1 superfamily)
   barrel, closed or opened; n=8, S=12; meander

4. Superfamily b.60.1: Lipocalins [50814] (10 families)
   bind hydrophobic ligands in their interior

5. Family b.60.1.2: Fatty acid binding protein-like [50847] (18 proteins)
   ten-stranded meander beta-sheet folded upon itself
   relates to the common fold by opening the barrel and insertion of beta-hairpin

6. Protein Cellular retinoic-acid-binding protein (CRABP) [50861] (2 species)

7. Species Human (Homo sapiens), CRABP-II [TaxId:9606] [50862] (30 PDB entries)

8. Domain d3fa6a_: 3fa6 A: [175605]
   automated match to d1bm5a_
   complexed with lsr; mutant

Details for d3fa6a_

PDB Entry: 3fa6, 1.54 Å

PDB Description: crystal structure of the r132k:y134f:r111l:l121d:t54v mutant of cellular retinoic acid-binding protein ii complexed with c15-aldehyde (a retinal analog) at 1.54 angstrom resolution

PDB Compounds: (A:) Cellular retinoic acid-binding protein 2

SCOPe Domain Sequences for d3fa6a_:

Sequence; same for both SEQRES and ATOM records:

>d3fa6a_ b.60.1.2 (A:) Cellular retinoic-acid-binding protein (CRABP) {Human (Homo sapiens), CRABP-II [TaxId: 9606]}
pnfsgnwkiirsenfeellkvlgvnvmlrkiavaaaskpaveikqegdtfyikvsttvrt
teinfkvgeefeeqtvdgrpckslvkwesenkmvceqkllkgegpktswtleltndgeli
dtmtaddvvctkvfvre

Timeline for d3fa6a_:

• d3fa6a_ first appeared in SCOPe 2.01
  
• d3fa6a_ appears in SCOPe 2.02
  
• d3fa6a_ appears in SCOPe 2.04
  
• d3fa6a_ appears in the current release, SCOPe 2.08