Lineage for d3f5xc_ (3f5x C:)

  1. Root: SCOPe 2.07
  2. 2494617Class d: Alpha and beta proteins (a+b) [53931] (388 folds)
  3. 2542179Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2542180Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2542316Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2542927Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
    CMGC group; CDKs subfamily; serine/threonine kinase
  7. 2542928Species Human (Homo sapiens) [TaxId:9606] [88856] (402 PDB entries)
    Uniprot P24941
  8. 2543322Domain d3f5xc_: 3f5x C: [175508]
    Other proteins in same PDB: d3f5xb1, d3f5xb2, d3f5xd1, d3f5xd2
    automated match to d1aq1a_
    complexed with ezv, gol, so4

Details for d3f5xc_

PDB Entry: 3f5x (more details), 2.4 Å

PDB Description: CDK-2-Cyclin complex with indazole inhibitor 9 bound at its active site
PDB Compounds: (C:) Cell division protein kinase 2

SCOPe Domain Sequences for d3f5xc_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3f5xc_ d.144.1.7 (C:) Cyclin-dependent PK, CDK2 {Human (Homo sapiens) [TaxId: 9606]}
menfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkelnh
pnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafchs
hrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgckyy
stavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykpsf
pkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlrl

SCOPe Domain Coordinates for d3f5xc_:

Click to download the PDB-style file with coordinates for d3f5xc_.
(The format of our PDB-style files is described here.)

Timeline for d3f5xc_: