SCOPe 2.03: Domain d3epxb_: 3epx B:

Lineage for d3epxb_ (3epx B:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.70: Nucleoside hydrolase [53589] (1 superfamily)
   core: 3 layers, a/b/a ; mixed beta-sheet of 8 strands, order 32145687; strand 7 is antiparallel to the rest

4. Superfamily c.70.1: Nucleoside hydrolase [53590] (2 families)

5. Family c.70.1.1: Nucleoside hydrolase [53591] (5 proteins)
   automatically mapped to Pfam PF01156

6. Protein automated matches [190287] (2 species)
   not a true protein

7. Species Trypanosoma vivax [TaxId:5699] [187091] (5 PDB entries)

8. Domain d3epxb_: 3epx B: [175151]
   automated match to d1hoza_
   complexed with ca, gol, imq

Details for d3epxb_

PDB Entry: 3epx, 1.85 Å

PDB Description: Crystal structure of Trypanosoma vivax nucleoside hydrolase in complex with the inhibitor (2R,3R,4S)-2-(hydroxymethyl)-1-(quinolin-8-ylmethyl)pyrrolidin-3,4-diol

PDB Compounds: (B:) IAG-nucleoside hydrolase

SCOPe Domain Sequences for d3epxb_:

Sequence, based on SEQRES records:

>d3epxb_ c.70.1.1 (B:) automated matches {Trypanosoma vivax [TaxId: 5699]}
aknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnnm
nlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqqll
adlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstdg
taewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgtm
wamcthcellrdgdgyyawdaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaen
ypltfvarnpeaeffldmllrsarac

Sequence, based on observed residues (ATOM records):

>d3epxb_ c.70.1.1 (B:) automated matches {Trypanosoma vivax [TaxId: 5699]}
aknvvldhdgnlddfvamvllasntekvrligalctdadcfvengfnvtgkimclmhnnm
nlplfpigksaatavnpfpkewrclaknmddmpilnipenvelwdkikaenekyegqqll
adlvmnseekvticvtgplsnvawcidkygekftskveecvimggavdvrgnvflpstdg
taewniywdpasaktvfgcpglrrimfsldstntvpvrspyvqrfgeqtnfllsilvgtm
wamcthcellrdgyyawdaltaayvvdqkvanvdpvpidvvvdkqpnegatvrtdaenyp
ltfvarnpeaeffldmllrsarac

Timeline for d3epxb_:

• d3epxb_ first appeared in SCOPe 2.01
  
• d3epxb_ appears in SCOPe 2.02
  
• d3epxb_ appears in SCOPe 2.04
  
• d3epxb_ appears in the current release, SCOPe 2.08