SCOPe 2.06: Domain d3e45a_: 3e45 A:

Lineage for d3e45a_ (3e45 A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.52: Restriction endonuclease-like [52979] (4 superfamilies)
   core: 3 layers, a/b/a; mixed beta-sheet of 5 strands, order 12345; strands 2 &, in some families, 5 are antiparallel to the rest

4. Superfamily c.52.1: Restriction endonuclease-like [52980] (36 families)

5. Family c.52.1.19: Restriction endonuclease HincII [69525] (1 protein)
   automatically mapped to Pfam PF09226

6. Protein Restriction endonuclease HincII [69526] (1 species)

7. Species Haemophilus influenzae [TaxId:727] [69527] (19 PDB entries)
   Uniprot P17743 ! Uniprot P44413

8. Domain d3e45a_: 3e45 A: [174645]
   automated match to d1kc6a_
   protein/DNA complex; complexed with ca, na

Details for d3e45a_

PDB Entry: 3e45, 2.78 Å

PDB Description: q138f hincii bound to noncognate dna (gtgcac) and ca2+

PDB Compounds: (A:) Type-2 restriction enzyme HindII

SCOPe Domain Sequences for d3e45a_:

Sequence, based on SEQRES records:

>d3e45a_ c.52.1.19 (A:) Restriction endonuclease HincII {Haemophilus influenzae [TaxId: 727]}
sfikpiyqdinsiligqkvkrpksgtlsghaagepfeklvykflkenlsdltfkqyeyln
dlfmknpaiighearyklfnsptllfllsrgkaatenwsienlfeekqndtadillvkdq
fyelldvktrnisksafapniisayklaqtcakmidnkefdlfdinylevdwelngedlv
cvstsfaelfksepselyinwaaamqiqfhvrdldqgfngtreewaksylkhfvtqaeqr
aismidkfvkpfkkyil

Sequence, based on observed residues (ATOM records):

>d3e45a_ c.52.1.19 (A:) Restriction endonuclease HincII {Haemophilus influenzae [TaxId: 727]}
sfikpiyqdinsiligqkvkrgepfeklvykflkenlsdltfkqyeylndlfmknpaiig
hearyklfnsptllfllsrgkaatenwsienlfeekqndtadillvkdqfyelldvktrn
isksafapniisayklaqtcakmidnkefdlfdinylevdwelngedlvcvstsfaelfk
sepselyinwaaamqiqfhvrdldqgfngtreewaksylkhfvtqaeqraismidkfvkp
fkkyil

Timeline for d3e45a_:

• d3e45a_ first appeared in SCOPe 2.01
  
• d3e45a_ appears in SCOPe 2.05
  
• d3e45a_ appears in SCOPe 2.07
  
• d3e45a_ appears in the current release, SCOPe 2.08