SCOPe 2.01: Domain d2y5kd_: 2y5k D:

Lineage for d2y5kd_ (2y5k D:)

1. Root: SCOPe 2.01

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.7: Carbohydrate phosphatase [56654] (1 superfamily)
   N-terminal domain is an alpha+beta, C-terminal domain is an alpha/beta with mixed beta-sheet

4. Superfamily e.7.1: Carbohydrate phosphatase [56655] (3 families)

5. Family e.7.1.1: Inositol monophosphatase/fructose-1,6-bisphosphatase-like [56656] (7 proteins)

6. Protein automated matches [190281] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187709] (12 PDB entries)

8. Domain d2y5kd_: 2y5k D: [170622]
   automated match to d1ftaa_
   complexed with ycu

Details for d2y5kd_

PDB Entry: 2y5k, 2.1 Å

PDB Description: orally active aminopyridines as inhibitors of tetrameric fructose 1,6-bisphosphatase

PDB Compounds: (D:) Fructose-1,6-bisphosphatase 1

SCOPe Domain Sequences for d2y5kd_:

Sequence, based on SEQRES records:

>d2y5kd_ e.7.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dvntltrfvmeegrkargtgeltqllnslctavkaissavrkagiahlygiagstnvtgd
qvkkldvlsndlvmnmlkssfatcvlvseedkhaiivepekrgkyvvcfdpldgssnidc
lvsvgtifgiyrkkstdepsekdalqpgrnlvaagyalygsatmlvlamdcgvncfmldp
aigefilvdkdvkikkkgkiyslnegyakdfdpavteyiqrkkfppdnsapygaryvgsm
vadvhrtlvyggiflypankkspngklrllyecnpmayvmekaggmattgkeavldvipt
dihqrapvilgspddvleflkvyekhsa

Sequence, based on observed residues (ATOM records):

>d2y5kd_ e.7.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dvntltrfvmeegrkargtgeltqllnslctavkaissavrkagiahlygiagkldvlsn
dlvmnmlkssfatcvlvseedkhaiivepekrgkyvvcfdpldgssnidclvsvgtifgi
yrkkstdepsekdalqpgrnlvaagyalygsatmlvlamdcgvncfmldpaigefilvdk
dvkikkkgkiyslnegyakdfdpavteyiqrkkfppdnsapygaryvgsmvadvhrtlvy
ggiflypankkspngklrllyecnpmayvmekaggmattgkeavldviptdihqrapvil
gspddvleflkvyekhsa

Timeline for d2y5kd_:

• d2y5kd_ is new in SCOPe 2.01-stable
  
• d2y5kd_ appears in SCOPe 2.02
  
• d2y5kd_ appears in the current release, SCOPe 2.08