Lineage for d2pqka_ (2pqk A:)

  1. Root: SCOPe 2.04
  2. 1695624Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)
  3. 1695625Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
    multi-helical domains of various folds which is thought to unfold in the membrane
  4. 1695694Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families) (S)
    PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain
  5. 1695695Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
    Pfam PF00452
  6. 1695790Protein EAT/MCL-1 (Myeloid cell leukemia sequence 1) [118212] (3 species)
  7. 1695791Species Human (Homo sapiens) [TaxId:9606] [188549] (1 PDB entry)
  8. 1695792Domain d2pqka_: 2pqk A: [167245]
    automated match to d1wsxa_
    complexed with na, zn

Details for d2pqka_

PDB Entry: 2pqk (more details), 2 Å

PDB Description: x-ray crystal structure of human mcl-1 in complex with bim bh3
PDB Compounds: (A:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d2pqka_:

Sequence, based on SEQRES records: (download)

>d2pqka_ f.1.4.1 (A:) EAT/MCL-1 (Myeloid cell leukemia sequence 1) {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d2pqka_ f.1.4.1 (A:) EAT/MCL-1 (Myeloid cell leukemia sequence 1) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d2pqka_:

Click to download the PDB-style file with coordinates for d2pqka_.
(The format of our PDB-style files is described here.)

Timeline for d2pqka_: