SCOPe 2.04: Domain d2oprb_: 2opr B:

Lineage for d2oprb_ (2opr B:)

1. Root: SCOPe 2.04

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.8: DNA/RNA polymerases [56671] (1 superfamily)
   divided into morphological domains including "palm", "thumb" and "fingers"; the catalytic "palm" domain is conserved to all members

4. Superfamily e.8.1: DNA/RNA polymerases [56672] (7 families)
   "palm" domain has a ferredoxin-like fold, related to that of an adenylyl cyclase domain

5. Family e.8.1.2: Reverse transcriptase [56686] (3 proteins)

6. Protein HIV-1 reverse transcriptase [56689] (3 species)

7. Species Hiv-1 m:b_hxb2r [TaxId:11706] [190022] (22 PDB entries)

8. Domain d2oprb_: 2opr B: [166819]
   Other proteins in same PDB: d2opra2
   automated match to d1c0ub_
   complexed with hbq; mutant

Details for d2oprb_

PDB Entry: 2opr, 2.9 Å

PDB Description: crystal structure of k101e mutant hiv-1 reverse transcriptase in complex with gw420867x.

PDB Compounds: (B:) p51 RT

SCOPe Domain Sequences for d2oprb_:

Sequence, based on SEQRES records:

>d2oprb_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Hiv-1 m:b_hxb2r [TaxId: 11706]}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfwevqlgiphpaglekkksvtvldvgdayfsvpldedfr
kytaftipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymd
dlyvgsdleigqhrtkieelrqhllrwglttpdkkhqkeppflwmgyelhpdkwtvqpiv
lpekdswtvndiqklvgklnwasqiypgikvrqlckllrgtkalteviplteeaelelae
nreilkepvhgvyydpskdliaeiqkqgqgqwtyqiyqepfknlktgkyarmrgahtndv
kqlteavqkittesiviwgktpkfklpiqketwetwwteywqatwipewefvntpplvkl
wyqlek

Sequence, based on observed residues (ATOM records):

>d2oprb_ e.8.1.2 (B:) HIV-1 reverse transcriptase {Hiv-1 m:b_hxb2r [TaxId: 11706]}
etvpvklkpgmdgpkvkqwplteekikalveictemekegkiskigpenpyntpvfaikk
kdstkwrklvdfrelnkrtqdfiphpaglekkksvtvldvgdayfsvpldedfrkytaft
ipsinnetpgiryqynvlpqgwkgspaifqssmtkilepfrkqnpdiviyqymddlyvgs
dleigqhrtkieelrqhllrwelhpdkwtvqpivlpekdswtvndiqklvgklnwasqiy
pgikvrqlckllrgtkalteviplteeaelelaenreilkepvhgvyydpskdliaeiqk
qgqgqwtyqiyqepfknlktgkyarmrgahtndvkqlteavqkittesiviwgktpkfkl
piqketwetwwteywqatwipewefvntpplvklwyqlek

Timeline for d2oprb_:

• d2oprb_ first appeared in SCOPe 2.01
  
• d2oprb_ appears in SCOPe 2.03
  
• d2oprb_ appears in SCOPe 2.05
  
• d2oprb_ appears in the current release, SCOPe 2.08