SCOPe 2.05: Domain d2fied_: 2fie D:

Lineage for d2fied_ (2fie D:)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.7: Carbohydrate phosphatase [56654] (1 superfamily)
   N-terminal domain is an alpha+beta, C-terminal domain is an alpha/beta with mixed beta-sheet

4. Superfamily e.7.1: Carbohydrate phosphatase [56655] (3 families)

5. Family e.7.1.1: Inositol monophosphatase/fructose-1,6-bisphosphatase-like [56656] (7 proteins)

6. Protein automated matches [190281] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187709] (17 PDB entries)

8. Domain d2fied_: 2fie D: [164398]
   automated match to d1ftaa_
   complexed with a74

Details for d2fied_

PDB Entry: 2fie, 2.81 Å

PDB Description: structure of human liver fbpase complexed with potent benzoxazole allosteric inhibitors

PDB Compounds: (D:) Fructose-1,6-bisphosphatase 1

SCOPe Domain Sequences for d2fied_:

Sequence, based on SEQRES records:

>d2fied_ e.7.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dvntltrfvmeegrkargtgeltqllnslctavkaissavrkagiahlygiagstnvtgd
qvkkldvlsndlvmnmlkssfatcvlvseedkhaiivepekrgkyvvcfdpldgssnidc
lvsvgtifgiyrkkstdepsekdalqpgrnlvaagyalygsatmlvlamdcgvncfmldp
aigefilvdkdvkikkkgkiyslnegyakdfdpavteyiqrkkfppdnsapygaryvgsm
vadvhrtlvyggiflypankkspngklrllyecnpmayvmekaggmattgkeavldvipt
dihqrapvilgspddvleflkvyekhsa

Sequence, based on observed residues (ATOM records):

>d2fied_ e.7.1.1 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dvntltrfvmeegrkargtgeltqllnslctavkaissavrkagiahlygiagskldvls
ndlvmnmlkssfatcvlvseedkhaiivepekrgkyvvcfdpldgssnidclvsvgtifg
iyrkkstdepsekdalqpgrnlvaagyalygsatmlvlamdcgvncfmldpaigefilvd
kdvkikkkgkiyslnegyakdfdpavteyiqrkkfppdnsapygaryvgsmvadvhrtlv
yggiflypankkspngklrllyecnpmayvmekaggmattgkeavldviptdihqrapvi
lgspddvleflkvyekhsa

Timeline for d2fied_:

• d2fied_ first appeared in SCOPe 2.01
  
• d2fied_ appears in SCOPe 2.04
  
• d2fied_ appears in SCOPe 2.06
  
• d2fied_ appears in the current release, SCOPe 2.08