Lineage for d2a3ka_ (2a3k A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2875105Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
    core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423
  4. 2875106Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families) (S)
    share with the family I the common active site structure with a circularly permuted topology
  5. 2875255Family c.45.1.2: Higher-molecular-weight phosphotyrosine protein phosphatases [52805] (7 proteins)
    has an extension to the beta-sheet of 3 antiparallel strands before strand 4
  6. 2875600Protein automated matches [190252] (5 species)
    not a true protein
  7. 2875603Species Human (Homo sapiens) [TaxId:9606] [187034] (47 PDB entries)
  8. 2875639Domain d2a3ka_: 2a3k A: [162660]
    automated match to d1jlna_
    complexed with po4

Details for d2a3ka_

PDB Entry: 2a3k (more details), 2.55 Å

PDB Description: Crystal Structure of the Human Protein Tyrosine Phosphatase, PTPN7 (HePTP, Hematopoietic Protein Tyrosine Phosphatase)
PDB Compounds: (A:) protein tyrosine phosphatase, non-receptor type 7, isoform 1

SCOPe Domain Sequences for d2a3ka_:

Sequence, based on SEQRES records: (download)

>d2a3ka_ c.45.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ntprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvspedldipghaskdr
yktilpnpqsrvclgraqsqedgdyinanyirgydgkekvyiatqgpmpntvsdfwemvw
qeevslivmltqlregkekcvhywpteeetygpfqiriqdmkecpeytvrqltiqyqeer
rsvkhilfsawpdhqtpesagpllrlvaeveespetaahpgpivvhcsagigrtgcfiat
rigcqqlkargevdilgivcqlrldrggmiqtaeqyqflhhtlalyagqlpeep

Sequence, based on observed residues (ATOM records): (download)

>d2a3ka_ c.45.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ntprevtlhflrtaghpltrwalqrqppspkqleeeflkipsnfvspedldipghaskdr
yktilpnpqsrvclgdyinanyirgydgkekvyiatqgpmpntvsdfwemvwqeevsliv
mltqlrvhywpteeetygpfqiriqdmkecpeytvrqltiqyqeerrsvkhilfsawpdh
qtpesagpllrlvaeveegpivvhcsagigrtgcfiatrigcqqlkargevdilgivcql
rldrggmiqtaeqyqflhhtlalyagqlpeep

SCOPe Domain Coordinates for d2a3ka_:

Click to download the PDB-style file with coordinates for d2a3ka_.
(The format of our PDB-style files is described here.)

Timeline for d2a3ka_: