SCOPe 2.08: Domain d3cs4a_: 3cs4 A:

Lineage for d3cs4a_ (3cs4 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein Vitamin D nuclear receptor [48528] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [48529] (30 PDB entries)

8. Domain d3cs4a_: 3cs4 A: [156954]
   automated match to d1ie9a_
   complexed with cov

Details for d3cs4a_

PDB Entry: 3cs4, 2 Å

PDB Description: Structure-based design of a superagonist ligand for the vitamin D nuclear receptor

PDB Compounds: (A:) Vitamin D3 receptor

SCOPe Domain Sequences for d3cs4a_:

Sequence; same for both SEQRES and ATOM records:

>d3cs4a_ a.123.1.1 (A:) Vitamin D nuclear receptor {Human (Homo sapiens) [TaxId: 9606]}
slrpklseeqqriiailldahhktydptysdfcqfrppvrvndgggsvtlelsqlsmlph
ladlvsysiqkvigfakmipgfrdltsedqivllkssaievimlrsnesftmddmswtcg
nqdykyrvsdvtkaghslelieplikfqvglkklnlheeehvllmaicivspdrpgvqda
alieaiqdrlsntlqtyircrhpppgshllyakmiqkladlrslneehskqyrclsfqpe
csmkltplvlevfg

Timeline for d3cs4a_:

• d3cs4a_ first appeared in SCOP 1.75, called d3cs4a1
  
• d3cs4a_ appears in SCOPe 2.07