SCOPe 2.06: Domain d3c0ob2: 3c0o B:85-468

Lineage for d3c0ob2 (3c0o B:85-468)

1. Root: SCOPe 2.06

2. Class f: Membrane and cell surface proteins and peptides [56835] (59 folds)

3. Fold f.8: Aerolisin/ETX pore-forming domain [56972] (1 superfamily)
   3 domains: (1) alpha+beta; (2&3) all-beta

4. Superfamily f.8.1: Aerolisin/ETX pore-forming domain [56973] (3 families)

5. Family f.8.1.1: (Pro)aerolysin, pore-forming lobe [56974] (2 proteins)
   automatically mapped to Pfam PF01117

6. Protein (Pro)aerolysin, pore-forming lobe [56975] (1 species)
   contains the APT module at the N-terminus

7. Species Aeromonas hydrophila [TaxId:644] [56976] (6 PDB entries)

8. Domain d3c0ob2: 3c0o B:85-468 [155838]
   Other proteins in same PDB: d3c0oa1, d3c0ob1
   automated match to d1prea2
   complexed with act, m6p; mutant

Details for d3c0ob2

PDB Entry: 3c0o, 2.5 Å

PDB Description: crystal structure of the proaerolysin mutant y221g complexed with mannose-6-phosphate

PDB Compounds: (B:) Aerolysin

SCOPe Domain Sequences for d3c0ob2:

Sequence, based on SEQRES records:

>d3c0ob2 f.8.1.1 (B:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
iptlsaldipdgdevdvqwrlvhdsanfikptsylahylgyawvggnhsqyvgedmdvtr
dgdgwvirgnndggcdgyrcgdktaikvsnfaynldpdsfkhgdvtqsdrqlvktvvgwa
vndsdtpqsgydvtlrgdtatnwsktntyglsekvttknkfkwplvgetelsieiaanqs
wasqnggstttslsqsvrptvparskipvkielykadisypyefkadvsydltlsgflrw
ggnawythpdnrpnwnhtfvigpykdkassiryqwdkryipgevkwwdwnwtiqqnglst
mqnnlarvlrpvragitgdfsaesqfagnieigapvplaadskvrrarsvdgagqglrle
ipldaqelsglgfnnvslsvtpaa

Sequence, based on observed residues (ATOM records):

>d3c0ob2 f.8.1.1 (B:85-468) (Pro)aerolysin, pore-forming lobe {Aeromonas hydrophila [TaxId: 644]}
iptlsaldipdgdevdvqwrlvhdsanfikptsylahylgyawvggnhsqyvgedmdvtr
dgdgwvirgnndggcdgyrcgdktaikvsnfaynldpdsfkhgdvtqsdrqlvktvvgwa
vndsdtpqsgydvtlrgdtatnwsktntyglsekvttknkfkwplvgetelsieiaanqs
wasqnggstttslsqsvrptvparskipvkielykadisypyefkadvsydltlsgflrw
ggnawythpdnrpnwnhtfvigpykdkassiryqwdkryipgevkwwdwnwtiqqnglst
mqnnlarvlrpvragitgdfsaesqfagnieigapvplglrleipldaqelsglgfnnvs
lsvtpaa

Timeline for d3c0ob2:

• d3c0ob2 first appeared in SCOP 1.75
  
• d3c0ob2 appears in SCOPe 2.05
  
• d3c0ob2 appears in SCOPe 2.07
  
• d3c0ob2 appears in the current release, SCOPe 2.08