SCOPe 2.05: Domain d2z0pa_: 2z0p A:

Lineage for d2z0pa_ (2z0p A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.55: PH domain-like barrel [50728] (2 superfamilies)
   barrel, partly opened; n*=6, S*=12; meander; capped by an alpha-helix

4. Superfamily b.55.1: PH domain-like [50729] (14 families)

5. Family b.55.1.1: Pleckstrin-homology domain (PH domain) [50730] (48 proteins)
   Pfam PF00169

6. Protein automated matches [190063] (3 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187187] (8 PDB entries)

8. Domain d2z0pa_: 2z0p A: [153912]
   automated match to d1b55a_
   complexed with 4pt, zn

Details for d2z0pa_

PDB Entry: 2z0p, 2.58 Å

PDB Description: crystal structure of ph domain of bruton's tyrosine kinase

PDB Compounds: (A:) Tyrosine-protein kinase BTK

SCOPe Domain Sequences for d2z0pa_:

Sequence, based on SEQRES records:

>d2z0pa_ b.55.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aavilesiflkrsqqkkktsplnfkkrlflltvhklsyyeydfergrrgskkgsidveki
tcvetvvpeknppperqiprrgeessemeqisiierfpypfqvvydegplyvfspteelr
krwihqlknvirynsdlvqkyhpcfwidgqylccsqtaknamgcqil

Sequence, based on observed residues (ATOM records):

>d2z0pa_ b.55.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aavilesiflkrsqqkkktsplnfkkrlflltvhklsyyeydfergrrgskkgsidveki
tcvetvvpeknppperqimeqisiierfpypfqvvydegplyvfspteelrkrwihqlkn
virynsdlvqkyhpcfwidgqylccsqtaknamgcqil

Timeline for d2z0pa_:

• d2z0pa_ first appeared in SCOP 1.75, called d2z0pa1
  
• d2z0pa_ appears in SCOPe 2.04
  
• d2z0pa_ appears in SCOPe 2.06
  
• d2z0pa_ appears in the current release, SCOPe 2.08