SCOPe 2.08: Domain d2rgra_: 2rgr A:

Lineage for d2rgra_ (2rgr A:)

1. Root: SCOPe 2.08

2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)

3. Fold e.11: Type II DNA topoisomerase C-terminal domain-like [56718] (1 superfamily)
   4 domains: (1) toprim alpha/beta; (2) "winged helix"-like; (3) alpha+beta; (4) all-alpha

4. Superfamily e.11.1: Type II DNA topoisomerase C-terminal domain-like [56719] (2 families)

5. Family e.11.1.1: Type II DNA topoisomerase C-terminal domain-like [56720] (3 proteins)
   domain 2 contains the catalytic tyrosine residue

6. Protein DNA topoisomerase II, C-terminal fragment (residues 410-1202) [56721] (1 species)
   the N-terminal fragment is homologous to known structure of DNA gyrase B

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56722] (3 PDB entries)

8. Domain d2rgra_: 2rgr A: [152021]
   automated match to d1bgwa_
   protein/DNA complex; complexed with mg
   has additional subdomain(s) that are not in the common domain

Details for d2rgra_

PDB Entry: 2rgr, 3 Å

PDB Description: topoisomerase iia bound to g-segment dna

PDB Compounds: (A:) DNA topoisomerase 2

SCOPe Domain Sequences for d2rgra_:

Sequence, based on SEQRES records:

>d2rgra_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
rksritnypkledankagtkegykctlvltegdsalslavaglavvgrdyygcyplrgkm
lnvreasadqilknaeiqaikkimglqhrkkyedtkslryghlmimtdqdhdgshikgli
inflessflglldiqgfllefitpiikvsitkptkntiafynmpdyekwreeeshkftwk
qkyykglgtslaqevreyfsnldrhlkifhslqgndkdyidlafskkkaddrkewlrqye
pgtvldptlkeipisdfinkelilfsladnirsipnvldgfkpgqrkvlygcfkknlkse
lkvaqlapyvsectayhhgeqslaqtiiglaqnfvgsnniylllpngafgtratggkdaa
aaryiytelnkltrkifhpaddplykyiqedektvepewylpilpmilvngaegigtgws
tyippfnpleiiknirhlmndeeleqmhpwfrgwtgtieeieplryrmygrieqigdnvl
eitelpartwtstikeylllglsgndkikpwikdmeeqhddnikfiitlspeemaktrki
gfyerfklispislmnmvafdphgkikkynsvneilsefyyvrleyyqkrkdhmserlqw
evekysfqvkfikmiiekeltvtnkprnaiiqelenlgfprfnkegkpyygspndeiaeq
indvkgatsdeedeesshedtenvingpeelygtyeyllgmriwsltkeryqkllkqkqe
ketelenllklsakdiwntdlkafevgyqeflqrdaear

Sequence, based on observed residues (ATOM records):

>d2rgra_ e.11.1.1 (A:) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
rksritnypkledankagtkegykctlvltegdsalslavaglavvgrdyygcyplrgkm
lnvreasadqilknaeiqaikkimglqhrkkyedtkslryghlmimtdqdhdgshikgli
inflessflglldiqgfllefitpiikvsitkptkntiafynmpdyekwreeeshkftwk
qkyykglgtslaqevreyfsnldrhlkifhslqgndkdyidlafskkkaddrkewlrqye
pgtvldptlkeipisdfinkelilfsladnirsipnvldgfkpgqrkvlygcfkknlkse
lkvaqlapyvsectayhhgeqslaqtiiglaqnfvgsnniylllpngafgtratggkdaa
aaryiytelnkltrkifhpaddplykyiqedektvepewylpilpmilvngaegigtgws
tyippfnpleiiknirhlmndeeleqmhpwfrgwtgtieeieplryrmygrieqigdnvl
eitelpartwtstikeylllglsgndkikpwikdmeeqhddnikfiitlspeemaktrki
gfyerfklispislmnmvafdphgkikkynsvneilsefyyvrleyyqkrkdhmserlqw
evekysfqvkfikmiiekeltvtnkprnaiiqelenlgfprfnkegkpyygslygtyeyl
lgmriwsltkeryqkllkqkqeketelenllklsakdiwntdlkafevgyqeflqrdaea
r

Timeline for d2rgra_:

• d2rgra_ first appeared in SCOP 1.75, called d2rgra1
  
• d2rgra_ appears in SCOPe 2.07