SCOP 1.75: Domain d2rgra1: 2rgr A:419-1177

Lineage for d2rgra1 (2rgr A:419-1177)

1. Root: SCOP 1.75

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.11: Type II DNA topoisomerase [56718] (1 superfamily)
   4 domains: (1) toprim alpha/beta; (2) "winged helix"-like; (3) alpha+beta; (4) all-alpha

4. Superfamily e.11.1: Type II DNA topoisomerase [56719] (1 family)

5. Family e.11.1.1: Type II DNA topoisomerase [56720] (2 proteins)
   domain 2 contains the catalytic tyrosine residue

6. Protein DNA topoisomerase II, C-terminal fragment (residues 410-1202) [56721] (1 species)
   the N-terminal fragment is homologous to known structure of DNA gyrase B

7. Species Baker's yeast (Saccharomyces cerevisiae) [TaxId:4932] [56722] (3 PDB entries)

8. Domain d2rgra1: 2rgr A:419-1177 [152021]
   automatically matched to d1bjta_
   complexed with mg

Details for d2rgra1

PDB Entry: 2rgr, 3 Å

PDB Description: topoisomerase iia bound to g-segment dna

PDB Compounds: (A:) DNA topoisomerase 2

SCOP Domain Sequences for d2rgra1:

Sequence, based on SEQRES records:

>d2rgra1 e.11.1.1 (A:419-1177) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
rksritnypkledankagtkegykctlvltegdsalslavaglavvgrdyygcyplrgkm
lnvreasadqilknaeiqaikkimglqhrkkyedtkslryghlmimtdqdhdgshikgli
inflessflglldiqgfllefitpiikvsitkptkntiafynmpdyekwreeeshkftwk
qkyykglgtslaqevreyfsnldrhlkifhslqgndkdyidlafskkkaddrkewlrqye
pgtvldptlkeipisdfinkelilfsladnirsipnvldgfkpgqrkvlygcfkknlkse
lkvaqlapyvsectayhhgeqslaqtiiglaqnfvgsnniylllpngafgtratggkdaa
aaryiytelnkltrkifhpaddplykyiqedektvepewylpilpmilvngaegigtgws
tyippfnpleiiknirhlmndeeleqmhpwfrgwtgtieeieplryrmygrieqigdnvl
eitelpartwtstikeylllglsgndkikpwikdmeeqhddnikfiitlspeemaktrki
gfyerfklispislmnmvafdphgkikkynsvneilsefyyvrleyyqkrkdhmserlqw
evekysfqvkfikmiiekeltvtnkprnaiiqelenlgfprfnkegkpyygspndeiaeq
indvkgatsdeedeesshedtenvingpeelygtyeyllgmriwsltkeryqkllkqkqe
ketelenllklsakdiwntdlkafevgyqeflqrdaear

Sequence, based on observed residues (ATOM records):

>d2rgra1 e.11.1.1 (A:419-1177) DNA topoisomerase II, C-terminal fragment (residues 410-1202) {Baker's yeast (Saccharomyces cerevisiae) [TaxId: 4932]}
rksritnypkledankagtkegykctlvltegdsalslavaglavvgrdyygcyplrgkm
lnvreasadqilknaeiqaikkimglqhrkkyedtkslryghlmimtdqdhdgshikgli
inflessflglldiqgfllefitpiikvsitkptkntiafynmpdyekwreeeshkftwk
qkyykglgtslaqevreyfsnldrhlkifhslqgndkdyidlafskkkaddrkewlrqye
pgtvldptlkeipisdfinkelilfsladnirsipnvldgfkpgqrkvlygcfkknlkse
lkvaqlapyvsectayhhgeqslaqtiiglaqnfvgsnniylllpngafgtratggkdaa
aaryiytelnkltrkifhpaddplykyiqedektvepewylpilpmilvngaegigtgws
tyippfnpleiiknirhlmndeeleqmhpwfrgwtgtieeieplryrmygrieqigdnvl
eitelpartwtstikeylllglsgndkikpwikdmeeqhddnikfiitlspeemaktrki
gfyerfklispislmnmvafdphgkikkynsvneilsefyyvrleyyqkrkdhmserlqw
evekysfqvkfikmiiekeltvtnkprnaiiqelenlgfprfnkegkpyygslygtyeyl
lgmriwsltkeryqkllkqkqeketelenllklsakdiwntdlkafevgyqeflqrdaea
r

Timeline for d2rgra1:

• d2rgra1 is new in SCOP 1.75
  
• d2rgra1 appears in SCOPe 2.01
  
• d2rgra1 appears in the current release, SCOPe 2.08, called d2rgra_