SCOPe 2.08: Domain d2qtaa3: 2qta A:701-886

Lineage for d2qtaa3 (2qta A:701-886)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.48: TK C-terminal domain-like [52921] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 13245, strand 1 is antiparallel to the rest

4. Superfamily c.48.1: TK C-terminal domain-like [52922] (4 families)

5. Family c.48.1.1: Transketolase C-terminal domain-like [52923] (2 proteins)

6. Protein Pyruvate dehydrogenase E1 component, C-domain [75239] (1 species)
   E1A and E1B fused together in a single-chain protein

7. Species Escherichia coli [TaxId:562] [75240] (8 PDB entries)

8. Domain d2qtaa3: 2qta A:701-886 [151335]
   Other proteins in same PDB: d2qtaa1, d2qtaa2, d2qtab1, d2qtab2
   automated match to d2ieaa3
   complexed with mg, tdp; mutant

Details for d2qtaa3

PDB Entry: 2qta, 1.85 Å

PDB Description: e. coli pyruvate dehydrogenase e1 component e401k mutant with thiamin diphosphate

PDB Compounds: (A:) Pyruvate dehydrogenase E1 component

SCOPe Domain Sequences for d2qtaa3:

Sequence; same for both SEQRES and ATOM records:

>d2qtaa3 c.48.1.1 (A:701-886) Pyruvate dehydrogenase E1 component, C-domain {Escherichia coli [TaxId: 562]}
mpegaeegirkgiykletiegskgkvqllgsgsilrhvreaaeilakdygvgsdvysvts
ftelardgqdcerwnmlhpletprvpyiaqvmndapavastdymklfaeqvrtyvpaddy
rvlgtdgfgrsdsrenlrhhfevdasyvvvaalgelakrgeidkkvvadaiakfnidadk
vnprla

Timeline for d2qtaa3:

• d2qtaa3 first appeared in SCOP 1.75
  
• d2qtaa3 appears in SCOPe 2.07