SCOPe 2.02: Domain d2ppbc1: 2ppb C:1-1119

Lineage for d2ppbc1 (2ppb C:1-1119)

1. Root: SCOPe 2.02

2. Class e: Multi-domain proteins (alpha and beta) [56572] (66 folds)

3. Fold e.29: beta and beta-prime subunits of DNA dependent RNA-polymerase [64483] (1 superfamily)
   Multidomain subunits of complex domain organization

4. Superfamily e.29.1: beta and beta-prime subunits of DNA dependent RNA-polymerase [64484] (2 families)
   The catalytic site is formed by the association of two double-psi beta-barrel domains, one from each subunit

5. Family e.29.1.1: RNA-polymerase beta [64485] (3 proteins)

6. Protein RNA-polymerase beta [64488] (2 species)

7. Species Thermus thermophilus [TaxId:274] [75609] (9 PDB entries)
   Uniprot Q8RQE9; part of multichain biological unit

8. Domain d2ppbc1: 2ppb C:1-1119 [149753]
   Other proteins in same PDB: d2ppbd1, d2ppbn1
   automatically matched to d1iw7c_
   protein/DNA complex; protein/RNA complex; complexed with apc, mg, std, zn

Details for d2ppbc1

PDB Entry: 2ppb, 3 Å

PDB Description: Crystal structure of the T. thermophilus RNAP polymerase elongation complex with the ntp substrate analog and antibiotic streptolydigin

PDB Compounds: (C:) DNA-directed RNA polymerase beta chain

SCOPe Domain Sequences for d2ppbc1:

Sequence; same for both SEQRES and ATOM records:

>d2ppbc1 e.29.1.1 (C:1-1119) RNA-polymerase beta {Thermus thermophilus [TaxId: 274]}
meikrfgrireviplpplteiqvesyrralqadvppekrenvgiqaafretfpieeedkg
kgglvldfleyrlgeppfpqdecrekdltyqaplyarlqlihkdtglikedevflghipl
mtedgsfiingadrvivsqihrspgvyftpdparpgryiasiiplpkrgpwidlevepng
vvsmkvnkrkfplvlllrvlgydqetlarelgaygelvqglmdesvfamrpeealirlft
llrpgdppkrdkavayvygliadprrydlgeagrykaeeklgirlsgrtlarfedgefkd
evflptlrylfaltagvpghevddidhlgnrrirtvgelmtdqfrvglarlargvrerml
mgsedsltpaklvnsrpleaaireffsrsqlsqfkdetnplsslrhkrrisalgpggltr
eragfdvrdvhrthygricpvetpeganiglitslaayarvdelgfirtpyrrvvggvvt
devvymtateedrytiaqantplegnriaaervvarrkgepvivspeevefmdvspkqvf
svntnlipflehddanralmgsnmqtqavpliraqapvvmtgleervvrdslaalyaeed
gevakvdgnrivvryedgrlveyplrrfyrsnqgtaldqrprvvvgqrvrkgdlladgpa
sengflalgqnvlvaimpfdgynfedaiviseellkrdfytsihieryeieardtklgpe
ritrdiphlseaalrdldeegvvrigaevkpgdilvgrtsfkgeseptpeerllrsifge
kardvkdtslrvppgeggivvrtvrlrrgdpgvelkpgvrevvrvyvaqkrklqvgdkla
nrhgnkgvvakilpvedmphlpdgtpvdvilnplgvpsrmnlgqilethlglagyflgqr
yispifdgakepeikellaqafevyfgkrkgegfgvdkrevevlrraeklglvtpgktpe
eqlkelflqgkvvlydgrtgepiegpivvgqmfimklyhmvedkmharstgpyslitqqp
lggkaqfggqrfgemevwaleaygaahtlqemltlksddiegrnaayeaiikgedvpeps
vpesfrvlvkelqalaldvqtldekdnpvdifeglaskr

Timeline for d2ppbc1:

• d2ppbc1 first appeared in SCOP 1.75
  
• d2ppbc1 appears in SCOPe 2.01
  
• d2ppbc1 appears in SCOPe 2.03
  
• d2ppbc1 appears in the current release, SCOPe 2.08, called d2ppbc_