SCOPe 2.07: Domain d2onyb2: 2ony B:514-780

Lineage for d2onyb2 (2ony B:514-780)

1. Root: SCOPe 2.07

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (60 families)

5. Family c.66.1.15: Arylamine N-methyltransferase [69547] (3 proteins)
   automatically mapped to Pfam PF01234

6. Protein automated matches [190168] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186895] (34 PDB entries)

8. Domain d2onyb2: 2ony B:514-780 [148916]
   Other proteins in same PDB: d2onyb3
   automated match to d1hnnb_
   complexed with po4, sah, tmj

Details for d2onyb2

PDB Entry: 2ony, 2.6 Å

PDB Description: Structure of hPNMT with inhibitor 7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy

PDB Compounds: (B:) Phenylethanolamine N-methyltransferase

SCOPe Domain Sequences for d2onyb2:

Sequence; same for both SEQRES and ATOM records:

>d2onyb2 c.66.1.15 (B:514-780) automated matches {Human (Homo sapiens) [TaxId: 9606]}
pdsapgqaavasayqrfepraylrnnyapprgdlcnpngvgpwklrclaqtfatgevsgr
tlidigsgptvyqllsacshfeditmtdflevnrqelgrwlqeepgafnwsmysqhacli
egkgecwqdkerqlrarvkrvlpidvhqpqplgagspaplpadalvsafcleavspdlas
fqraldhittllrpgghllligaleeswylagearltvvpvseeevrealvrsgykvrdl
rtyimpahlqtgvddvkgvffawaqkv

Timeline for d2onyb2:

• d2onyb2 first appeared in SCOP 1.75, called d2onyb1
  
• d2onyb2 was called d2onyb_ in SCOPe 2.06
  
• d2onyb2 appears in the current release, SCOPe 2.08