SCOPe 2.02: Domain d2e50a1: 2e50 A:1-222

Lineage for d2e50a1 (2e50 A:1-222)

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.305: NAP-like [143112] (1 superfamily)
   core: central meander 4-stranded beta-sheet (order: 1234) transversed by a C-terminal helix

4. Superfamily d.305.1: NAP-like [143113] (2 families)

5. Family d.305.1.1: NAP-like [143114] (2 proteins)
   Pfam PF00956

6. Protein Protein SET [160140] (1 species)
   Phosphatase 2A inhibitor I2PP2A

7. Species Human (Homo sapiens) [TaxId:9606] [160141] (1 PDB entry)
   Uniprot Q01105 1-235

8. Domain d2e50a1: 2e50 A:1-222 [146687]
   complexed with tre

Details for d2e50a1

PDB Entry: 2e50, 2.3 Å

PDB Description: crystal structure of set/taf-1beta/inhat

PDB Compounds: (A:) Protein SET

SCOPe Domain Sequences for d2e50a1:

Sequence, based on SEQRES records:

>d2e50a1 d.305.1.1 (A:1-222) Protein SET {Human (Homo sapiens) [TaxId: 9606]}
msaqaakvskkelnsnhdgadetsekeqqeaiehidevqneidrlneqaseeilkveqky
nklrqpffqkrseliakipnfwvttfvnhpqvsallgeedeeamhyltrvevtefediks
gyridfyfdenpyfenkvlskefhmnesgdpssksteikwksgkdmtkrssqtqnkasrk
rqheepesfftwftdhsdagadelgevikddiwpnplqyylv

Sequence, based on observed residues (ATOM records):

>d2e50a1 d.305.1.1 (A:1-222) Protein SET {Human (Homo sapiens) [TaxId: 9606]}
msaqaakvskkelnsdetsekeqqeaiehidevqneidrlneqaseeilkveqkynklrq
pffqkrseliakipnfwvttfvnhpqvsallgeedeeamhyltrvevtefediksgyrid
fyfdenpyfenkvlskefhssksteikwksgkdmfftwftadelgevikddiwpnplqyy
lv

Timeline for d2e50a1:

• d2e50a1 first appeared in SCOP 1.75
  
• d2e50a1 appears in SCOPe 2.01
  
• d2e50a1 appears in SCOPe 2.03
  
• d2e50a1 appears in the current release, SCOPe 2.08