SCOPe 2.07: Domain d2e2ra_: 2e2r A:

Lineage for d2e2ra_ (2e2r A:)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (2 families)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (34 proteins)

6. Protein automated matches [190059] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187214] (212 PDB entries)

8. Domain d2e2ra_: 2e2r A: [146654]
   automated match to d1tfca_
   complexed with 2oh, gol

Details for d2e2ra_

PDB Entry: 2e2r, 1.6 Å

PDB Description: Crystal structure of human estrogen-related receptor gamma ligand binding domain complex with bisphenol A

PDB Compounds: (A:) Estrogen-related receptor gamma

SCOPe Domain Sequences for d2e2ra_:

Sequence; same for both SEQRES and ATOM records:

>d2e2ra_ a.123.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kpynkivshllvaepekiyampdptvpdsdikalttlcdladrelvviigwakhipgfst
lsladqmsllqsawmeililgvvyrslsfedelvyaddyimdedqsklaglldlnnailq
lvkkyksmklekeefvtlkaialansdsmhiedveavqklqdvlhealqdyeagqhmedp
rragkmlmtlpllrqtstkavqhfyniklegkvpmhklflemleakvc

Timeline for d2e2ra_:

• d2e2ra_ first appeared in SCOP 1.75, called d2e2ra1
  
• d2e2ra_ appears in SCOPe 2.06
  
• d2e2ra_ appears in the current release, SCOPe 2.08