SCOPe 2.02: Family d.287.1.2: Type I restriction modification DNA specificity domain

Lineage for Family d.287.1.2: Type I restriction modification DNA specificity domain

1. Root: SCOPe 2.02

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.287: DNA methylase specificity domain [116733] (1 superfamily)
   comprises the N-terminal, double beta-helix like structure and C-terminal alpha-hairpin

4. Superfamily d.287.1: DNA methylase specificity domain [116734] (2 families)

5. Family d.287.1.2: Type I restriction modification DNA specificity domain [143979] (2 proteins)
   Pfam PF01420

Proteins:

1. Bipartite methylase S protein MG438 [143980] (1 species)
   duplication; contains two structural repeats made of this domain and extra C-terminal coiled coil each; overall structure is similar to MJ0130

   • Species Mycoplasma genitalium [TaxId:2097] [143981] (1 PDB entry)
     Uniprot Q49434 1-193! Uniprot Q49434 194-374

2. Bipartite methylase S protein MJ0130 [143982] (1 species)
   duplication: comprises two repeats of this domain, separated by a coiled coil made by additional long helices at the C-end of each repeat

   • Species Methanocaldococcus jannaschii [TaxId:2190] [143983] (1 PDB entry)
     Uniprot Q57594 1-220! Uniprot Q57594 221-425

More info for Family d.287.1.2: Type I restriction modification DNA specificity domain

Timeline for Family d.287.1.2: Type I restriction modification DNA specificity domain:

• Family d.287.1.2: Type I restriction modification DNA specificity domain first appeared in SCOP 1.73
  
• Family d.287.1.2: Type I restriction modification DNA specificity domain appears in SCOPe 2.01
  
• Family d.287.1.2: Type I restriction modification DNA specificity domain appears in SCOPe 2.03
  
• Family d.287.1.2: Type I restriction modification DNA specificity domain appears in the current release, SCOPe 2.08