SCOPe 2.08: Domain d2pg2a_: 2pg2 A:

Lineage for d2pg2a_ (2pg2 A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.9: Motor proteins [52641] (5 proteins)

6. Protein Kinesin [52646] (7 species)

7. Species Human (Homo sapiens), mitotic kinesin eg5 [TaxId:9606] [64018] (15 PDB entries)

8. Domain d2pg2a_: 2pg2 A: [139688]
   automated match to d1q0bb_
   complexed with adp, k01, mg

Details for d2pg2a_

PDB Entry: 2pg2, 1.85 Å

PDB Description: Crystal structure of KSP in complex with ADP and thiophene containing inhibitor 15

PDB Compounds: (A:) Kinesin-like protein KIF11

SCOPe Domain Sequences for d2pg2a_:

Sequence, based on SEQRES records:

>d2pg2a_ c.37.1.9 (A:) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
gkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgas
tkqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagi
iprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgvi
ikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeel
vkigklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphvpyresk
ltrilqdslggrtrtsiiatispaslnleetlstleyahraknilnk

Sequence, based on observed residues (ATOM records):

>d2pg2a_ c.37.1.9 (A:) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
gkniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgas
tkqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagi
iprtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgvi
ikgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeel
vkigklnlvdlagseninqslltlgrvitalvertphvpyreskltrilqdslggrtrts
iiatispaslnleetlstleyahraknilnk

Timeline for d2pg2a_:

• d2pg2a_ first appeared in SCOP 1.73, called d2pg2a1
  
• d2pg2a_ appears in SCOPe 2.07