SCOPe 2.03: Domain d2hv6b_: 2hv6 B:

Lineage for d2hv6b_ (2hv6 B:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.268: PTPA-like [140983] (1 superfamily)
   multihelical

4. Superfamily a.268.1: PTPA-like [140984] (1 family)
   automatically mapped to Pfam PF03095

5. Family a.268.1.1: PTPA-like [140985] (2 proteins)
   Pfam PF03095

6. Protein Serine/threonine-protein phosphatase 2A regulatory subunit B', PTPA [140986] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [140987] (4 PDB entries)
   Uniprot Q15257 22-322! Uniprot Q15257 23-322

8. Domain d2hv6b_: 2hv6 B: [136785]
   automated match to d2hv6a1
   complexed with mg

Details for d2hv6b_

PDB Entry: 2hv6, 1.9 Å

PDB Description: Crystal structure of the phosphotyrosyl phosphatase activator

PDB Compounds: (B:) Protein phosphatase 2A, regulatory subunit B

SCOPe Domain Sequences for d2hv6b_:

Sequence, based on SEQRES records:

>d2hv6b_ a.268.1.1 (B:) Serine/threonine-protein phosphatase 2A regulatory subunit B', PTPA {Human (Homo sapiens) [TaxId: 9606]}
nfiipkkeihtvpdmgkwkrsqayadyigfiltlnegvkgkkltfeyrvseaieklvall
ntldrwidetppvdqpsrfgnkayrtwyakldeeaenlvatvvpthlaaavpevavylke
svgnstridygtgheaafaaflcclckigvlrvddqiaivfkvfnrylevmrklqktyrm
epagsqgvwglddfqflpfiwgssqlidhpyleprhfvdekavnenhkdymflecilfit
emktgpfaehsnqlwnisavpswskvnqglirmykaeclekfpviqhfkfgsllpihpvt
s

Sequence, based on observed residues (ATOM records):

>d2hv6b_ a.268.1.1 (B:) Serine/threonine-protein phosphatase 2A regulatory subunit B', PTPA {Human (Homo sapiens) [TaxId: 9606]}
nfiipkkeihtvpdmgkwkrsqayadyigfiltlnegvkgkkltfeyrvseaieklvall
ntldrwidetppvdqpsrfgnkayrtwyakldeeaenlvatvvpthlaaavpevavylke
svgnstridygtgheaafaaflcclckigvlrvddqiaivfkvfnrylevmrklqktyrm
epaglddfqflpfiwgssqlidhpyleprhfvdekavnenhkdymflecilfitemktgp
faehsnqlwnisavpswskvnqglirmykaeclekfpviqhfkfgsllpihpvts

Timeline for d2hv6b_:

• d2hv6b_ first appeared in SCOP 1.73, called d2hv6b1
  
• d2hv6b_ was called d2hv6b1 in SCOPe 2.02
  
• d2hv6b_ appears in SCOPe 2.04
  
• d2hv6b_ appears in the current release, SCOPe 2.08