Lineage for d2gm1e_ (2gm1 E:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2111568Family c.37.1.9: Motor proteins [52641] (5 protein domains)
  6. 2111569Protein Kinesin [52646] (7 species)
  7. 2111576Species Human (Homo sapiens), mitotic kinesin eg5 [TaxId:9606] [64018] (13 PDB entries)
  8. 2111586Domain d2gm1e_: 2gm1 E: [135353]
    automated match to d1q0bb_
    complexed with 2az, adp, mg

Details for d2gm1e_

PDB Entry: 2gm1 (more details), 2.3 Å

PDB Description: crystal structure of the mitotic kinesin eg5 in complex with mg-adp and n-(3-aminopropyl)-n-((3-benzyl-5-chloro-4-oxo-3,4- dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)(cyclopropyl)methyl)-4- methylbenzamide
PDB Compounds: (E:) kinesin-related motor protein eg5

SCOPe Domain Sequences for d2gm1e_:

Sequence, based on SEQRES records: (download)

>d2gm1e_ c.37.1.9 (E:) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtggladkssrktytfdmvfgast
kqidvyrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagii
prtlhqifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgvii
kgleeitvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkettidgeelv
kigklnlvdlagsenigrsgavdkrareagninqslltlgrvitalvertphvpyreskl
trilqdslggrtrtsiiatispaslnleetlstleyahraknilnkpevnq

Sequence, based on observed residues (ATOM records): (download)

>d2gm1e_ c.37.1.9 (E:) Kinesin {Human (Homo sapiens), mitotic kinesin eg5 [TaxId: 9606]}
kniqvvvrcrpfnlaerkasahsivecdpvrkevsvrtgssrktytfdmvfgastkqidv
yrsvvcpildevimgynctifaygqtgtgktftmegerspneeytweedplagiiprtlh
qifekltdngtefsvkvslleiyneelfdllnpssdvserlqmfddprnkrgviikglee
itvhnkdevyqilekgaakrttaatlmnayssrshsvfsvtihmkvkigklnlvdlagse
nininqslltlgrvitalvertphvpyreskltrilqdslggrtrtsiiatispaslnle
etlstleyahraknilnkpevnq

SCOPe Domain Coordinates for d2gm1e_:

Click to download the PDB-style file with coordinates for d2gm1e_.
(The format of our PDB-style files is described here.)

Timeline for d2gm1e_: