SCOPe 2.03: Domain d2g8na_: 2g8n A:

Lineage for d2g8na_ (2g8n A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
   core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest

4. Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (58 families)

5. Family c.66.1.15: Arylamine N-methyltransferase [69547] (3 proteins)
   automatically mapped to Pfam PF01234

6. Protein automated matches [190168] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186895] (31 PDB entries)

8. Domain d2g8na_: 2g8n A: [134777]
   automated match to d1hnnb_
   complexed with f83, sah

Details for d2g8na_

PDB Entry: 2g8n, 2.15 Å

PDB Description: Structure of hPNMT with inhibitor 3-Hydroxymethyl-7-(N-4-chlorophenylaminosulfonyl)-THIQ and AdoHcy

PDB Compounds: (A:) Phenylethanolamine N-methyltransferase

SCOPe Domain Sequences for d2g8na_:

Sequence; same for both SEQRES and ATOM records:

>d2g8na_ c.66.1.15 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vasayqrfepraylrnnyapprgdlcnpngvgpwklrclaqtfatgevsgrtlidigsgp
tvyqllsacshfeditmtdflevnrqelgrwlqeepgafnwsmysqhacliegkgecwqd
kerqlrarvkrvlpidvhqpqplgagspaplpadalvsafcleavspdlasfqraldhit
tllrpgghllligaleeswylagearltvvpvseeevrealvrsgykvrdlrtyimpahl
qtgvddvkgvffawaqkv

Timeline for d2g8na_:

• d2g8na_ first appeared in SCOP 1.73, called d2g8na1
  
• d2g8na_ appears in SCOPe 2.02
  
• d2g8na_ appears in SCOPe 2.04
  
• d2g8na_ appears in the current release, SCOPe 2.08