SCOP 1.75: Domain d2ewpe1: 2ewp E:237-455

Lineage for d2ewpe1 (2ewp E:237-455)

1. Root: SCOP 1.75

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.123: Nuclear receptor ligand-binding domain [48507] (1 superfamily)
   multihelical; 3 layers or orthogonally packed helices

4. Superfamily a.123.1: Nuclear receptor ligand-binding domain [48508] (1 family)

5. Family a.123.1.1: Nuclear receptor ligand-binding domain [48509] (33 proteins)

6. Protein Orphan nuclear receptor ERR3 [81916] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [81917] (16 PDB entries)
   Uniprot O75454 233-458

8. Domain d2ewpe1: 2ewp E:237-455 [132492]
   automatically matched to d1tfca_
   complexed with txf

Details for d2ewpe1

PDB Entry: 2ewp, 2.3 Å

PDB Description: crystal structure of estrogen related receptor-3 (err-gamma) ligand binding domaind with tamoxifen analog gsk5182

PDB Compounds: (E:) Estrogen-related receptor gamma

SCOP Domain Sequences for d2ewpe1:

Sequence, based on SEQRES records:

>d2ewpe1 a.123.1.1 (E:237-455) Orphan nuclear receptor ERR3 {Human (Homo sapiens) [TaxId: 9606]}
ivshllvaepekiyampdptvpdsdikalttlcdladrelvviigwakhipgfstlslad
qmsllqsawmeililgvvyrslsfedelvyaddyimdedqsklaglldlnnailqlvkky
ksmklekeefvtlkaialansdsmhiedveavqklqdvlhealqdyeagqhmedprragk
mlmtlpllrqtstkavqhfyniklegkvpmhklflemle

Sequence, based on observed residues (ATOM records):

>d2ewpe1 a.123.1.1 (E:237-455) Orphan nuclear receptor ERR3 {Human (Homo sapiens) [TaxId: 9606]}
ivshllvaepekiyampdptvpdsdikalttlcdladrelvviigwakhipgfstlslad
qmsllqsawmeililgvvyrslsfedelvyaddyimdedqsklaglldlnnailqlvkky
ksmklekeefvtlkaialansdsmhiedveavqklqdvlhealqdyeedprragkmlmtl
pllrqtstkavqhfyniklegkvpmhklflemle

Timeline for d2ewpe1:

• d2ewpe1 first appeared in SCOP 1.73
  
• d2ewpe1 is called d2ewpe_ in SCOPe 2.01
  
• d2ewpe1 appears in the current release, SCOPe 2.08, called d2ewpe_