SCOPe 2.08: Domain d2etla1: 2etl A:1-223

Lineage for d2etla1 (2etl A:1-223)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-L [54050] (3 proteins)
   automatically mapped to Pfam PF01088

6. Protein Ubiquitin carboxyl-terminal hydrolase isozyme l1 [142856] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [142857] (4 PDB entries)
   Uniprot P09936 1-223

8. Domain d2etla1: 2etl A:1-223 [132361]
   Other proteins in same PDB: d2etlb_
   complexed with cl

Details for d2etla1

PDB Entry: 2etl, 2.4 Å

PDB Description: crystal structure of ubiquitin carboxy-terminal hydrolase l1 (uch-l1)

PDB Compounds: (A:) Ubiquitin carboxyl-terminal hydrolase isozyme L1

SCOPe Domain Sequences for d2etla1:

Sequence; same for both SEQRES and ATOM records:

>d2etla1 d.3.1.6 (A:1-223) Ubiquitin carboxyl-terminal hydrolase isozyme l1 {Human (Homo sapiens) [TaxId: 9606]}
mqlkpmeinpemlnkvlsrlgvagqwrfvdvlgleeeslgsvpapacallllfpltaqhe
nfrkkqieelkgqevspkvyfmkqtignscgtiglihavannqdklgfedgsvlkqflse
tekmspedrakcfekneaiqaahdavaqegqcrvddkvnfhfilfnnvdghlyeldgrmp
fpvnhgassedtllkdaakvcreftereqgevrfsavalckaa

Timeline for d2etla1:

• d2etla1 first appeared in SCOP 1.73
  
• d2etla1 appears in SCOPe 2.07