SCOPe 2.08: Family d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-L

Lineage for Family d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-L

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.3: Cysteine proteinases [54000] (1 superfamily)
   consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn

4. Superfamily d.3.1: Cysteine proteinases [54001] (24 families)
   the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet

5. Family d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-L [54050] (3 proteins)
   automatically mapped to Pfam PF01088

Proteins:

1. Ubiquitin carboxyl-terminal hydrolase isozyme l1 [142856] (1 species)

   • Species Human (Homo sapiens) [TaxId:9606] [142857] (4 PDB entries)
     Uniprot P09936 1-223

2. Ubiquitin carboxyl-terminal hydrolase UCH-l3 [54051] (2 species)

   1. Species Human (Homo sapiens) [TaxId:9606] [54052] (3 PDB entries)
      Uniprot P15374

   2. Species Synthetic, based on Saccharomyces cerevisiae sequence [54053] (1 PDB entry)

3. automated matches [191161] (1 species)
   not a true protein

   • Species Human (Homo sapiens) [TaxId:9606] [189359] (4 PDB entries)

More info for Family d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-L

Timeline for Family d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-L:

• Family d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-L first appeared (with stable ids) in SCOP 1.55, called Family d.3.1.6: Deubiquitinating enzyme
  
• Family d.3.1.6: Ubiquitin carboxyl-terminal hydrolase UCH-L appears in SCOPe 2.07