SCOPe 2.01: Domain d2ag4a_: 2ag4 A:

Lineage for d2ag4a_ (2ag4 A:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.95: Ganglioside M2 (gm2) activator [63706] (1 superfamily)
   sandwich; 8 strands in 2 sheets; greek-key: partial topological similarity to immunoglobulin-like folds

4. Superfamily b.95.1: Ganglioside M2 (gm2) activator [63707] (1 family)

5. Family b.95.1.1: Ganglioside M2 (gm2) activator [63708] (1 protein)

6. Protein Ganglioside M2 (gm2) activator [63709] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [63710] (8 PDB entries)
   Uniprot P17900 31-193

8. Domain d2ag4a_: 2ag4 A: [126717]
   automated match to d1pu5a_
   complexed with ipa, lp3, ola

Details for d2ag4a_

PDB Entry: 2ag4, 1.8 Å

PDB Description: Crystal Structure Analysis of GM2-activator protein complexed with phosphatidylcholine

PDB Compounds: (A:) Ganglioside GM2 activator

SCOPe Domain Sequences for d2ag4a_:

Sequence; same for both SEQRES and ATOM records:

>d2ag4a_ b.95.1.1 (A:) Ganglioside M2 (gm2) activator {Human (Homo sapiens) [TaxId: 9606]}
hmssfswdncdegkdpavirsltlepdpivvpgnvtlsvvgstsvplssplkvdlvleke
vaglwikipctdyigsctfehfcdvldmliptgepcpeplrtyglpchcpfkegtyslpk
sefvvpdlelpswlttgnyriesvlsssgkrlgcikiaaslkgi

Timeline for d2ag4a_:

• d2ag4a_ first appeared in SCOP 1.73, called d2ag4a1
  
• d2ag4a_ was called d2ag4a1 in SCOP 1.75
  
• d2ag4a_ appears in SCOPe 2.02
  
• d2ag4a_ appears in the current release, SCOPe 2.08, called d2ag4a2