SCOPe 2.06: Domain d2abwa1: 2abw A:2-219

Lineage for d2abwa1 (2abw A:2-219)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.23: Flavodoxin-like [52171] (15 superfamilies)
   3 layers, a/b/a; parallel beta-sheet of 5 strand, order 21345

4. Superfamily c.23.16: Class I glutamine amidotransferase-like [52317] (10 families)
   conserved positions of the oxyanion hole and catalytic nucleophile; different constituent families contain different additional structures

5. Family c.23.16.1: Class I glutamine amidotransferases (GAT) [52318] (12 proteins)
   contains a catalytic Cys-His-Glu triad

6. Protein Pyridoxine biosynthesis protein 2, Pdx2 [142068] (1 species)

7. Species Malaria parasite (Plasmodium falciparum) [TaxId:5833] [142069] (1 PDB entry)
   Uniprot Q5ND68 2-219

8. Domain d2abwa1: 2abw A:2-219 [126535]
   Other proteins in same PDB: d2abwa2, d2abwb2, d2abwb3
   complexed with pg4

Details for d2abwa1

PDB Entry: 2abw, 1.62 Å

PDB Description: glutaminase subunit of the plasmodial plp synthase (vitamin b6 biosynthesis)

PDB Compounds: (A:) Pdx2 protein

SCOPe Domain Sequences for d2abwa1:

Sequence, based on SEQRES records:

>d2abwa1 c.23.16.1 (A:2-219) Pyridoxine biosynthesis protein 2, Pdx2 {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
seitigvlslqgdfephinhfiklqipslniiqvrnvhdlglcdglvipggesttvrrcc
ayendtlynalvhfihvlkkpiwgtcagcillsknveniklysnfgnkfsfgglditicr
nfygsqndsficslniisdssafkkdltaacirapyireilsdevkvlatfshesygpni
iaaveqnnclgtvfhpellphtafqqyfyekvknykys

Sequence, based on observed residues (ATOM records):

>d2abwa1 c.23.16.1 (A:2-219) Pyridoxine biosynthesis protein 2, Pdx2 {Malaria parasite (Plasmodium falciparum) [TaxId: 5833]}
seitigvlslqgdfephinhfiklqipslniiqvrnvhdlglcdglvipggesttvrrcc
ayendtlynalvhfihvlkkpiwgtcagcillsknveniklysnfgnkfsfgglditicr
nfndsficslniisdssafkkdltaacirapyireilsdevkvlatfshesygpniiaav
eqnnclgtvfhpellphtafqqyfyekvknykys

Timeline for d2abwa1:

• d2abwa1 first appeared in SCOP 1.73
  
• d2abwa1 appears in SCOPe 2.05
  
• d2abwa1 appears in SCOPe 2.07
  
• d2abwa1 appears in the current release, SCOPe 2.08