SCOPe 2.08: Domain d1za3a2: 1za3 A:107-213

Lineage for d1za3a2 (1za3 A:107-213)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin light chain kappa constant domain, CL-kappa [88566] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88569] (147 PDB entries)
   including humanized antibodies (chimeric proteins with human constant domains)
   SQ NA # humanized antibody ! Uniprot P01834 # KAC_HUMAN Ig kappa chain C region ! SQ P01834 # KAC_HUMAN Ig kappa chain C region. ! SQ NA # engineered antibody

8. Domain d1za3a2: 1za3 A:107-213 [124788]
   Other proteins in same PDB: d1za3a1, d1za3b1, d1za3b2, d1za3h1, d1za3h2, d1za3l1, d1za3r1, d1za3r2, d1za3r3, d1za3s1, d1za3s2, d1za3s3
   automatically matched to d1c5da2

Details for d1za3a2

PDB Entry: 1za3, 3.35 Å

PDB Description: The crystal structure of the YSd1 Fab bound to DR5

PDB Compounds: (A:) Fab-YSd1 light chain

SCOPe Domain Sequences for d1za3a2:

Sequence; same for both SEQRES and ATOM records:

>d1za3a2 b.1.1.2 (A:107-213) Immunoglobulin light chain kappa constant domain, CL-kappa {Human (Homo sapiens) [TaxId: 9606]}
rtvaapsvfifppsdeqlksgtasvvcllnnfypreakvqwkvdnalqsgnsqesvteqd
skdstyslsstltlskadyekhkvyacevthqglsspvtksfnrgec

Timeline for d1za3a2:

• d1za3a2 first appeared in SCOP 1.73
  
• d1za3a2 appears in SCOPe 2.07