SCOP 1.73: Domain d1y2cb1: 1y2c B:86-411

Lineage for d1y2cb1 (1y2c B:86-411)

1. Root: SCOP 1.73

2. Class a: All alpha proteins [46456] (258 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (5 families)

5. Family a.211.1.2: PDEase [48548] (6 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein Catalytic domain of cyclic nucleotide phosphodiesterase pde4d [89151] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89152] (20 PDB entries)

8. Domain d1y2cb1: 1y2c B:86-411 [122559]
   automatically matched to d1oyna_
   complexed with 3de, edo, mg, zn

Details for d1y2cb1

PDB Entry: 1y2c, 1.67 Å

PDB Description: Catalytic Domain Of Human Phosphodiesterase 4D In Complex With 3,5-dimethyl-1-phenyl-1H-pyrazole-4-carboxylic acid ethyl ester

PDB Compounds: (B:) cAMP-specific 3',5'-cyclic phosphodiesterase 4D

SCOP Domain Sequences for d1y2cb1:

Sequence; same for both SEQRES and ATOM records:

>d1y2cb1 a.211.1.2 (B:86-411) Catalytic domain of cyclic nucleotide phosphodiesterase pde4d {Human (Homo sapiens) [TaxId: 9606]}
teqedvlakeledvnkwglhvfriaelsgnrpltvimhtifqerdllktfkipvdtlity
lmtledhyhadvayhnnihaadvvqsthvllstpaleavftdleilaaifasaihdvdhp
gvsnqflintnselalmyndssvlenhhlavgfkllqeencdifqnltkkqrqslrkmvi
divlatdmskhmnlladlktmvetkkvtssgvllldnysdriqvlqnmvhcadlsnptkp
lqlyrqwtdrimeeffrqgdrerergmeispmcdkhnasveksqvgfidyivhplwetwa
dlvhpdaqdildtlednrewyqstip

Timeline for d1y2cb1:

• d1y2cb1 is new in SCOP 1.73
  
• d1y2cb1 appears in SCOP 1.75
  
• d1y2cb1 appears in the current release, SCOPe 2.08, called d1y2cb_