SCOP 1.75: Domain d1u3wb1: 1u3w B:1-162,B:339-374

Lineage for d1u3wb1 (1u3w B:1-162,B:339-374)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.35: GroES-like [50128] (2 superfamilies)
   contains barrel, partly opened; n*=4, S*=8; meander

4. Superfamily b.35.1: GroES-like [50129] (2 families)

5. Family b.35.1.2: Alcohol dehydrogenase-like, N-terminal domain [50136] (15 proteins)
   C-terminal domain is alpha/beta (classical Rossmann-fold)

6. Protein Alcohol dehydrogenase [50137] (9 species)
   contains a Zn-finger subdomain, residues 94-117

7. Species Human (Homo sapiens), different isozymes [TaxId:9606] [50139] (24 PDB entries)
   Uniprot P00326
   Uniprot P00325
   Uniprot P07327
   Uniprot P00326 ! Uniprot P00325 ! Uniprot P07327

8. Domain d1u3wb1: 1u3w B:1-162,B:339-374 [113015]
   Other proteins in same PDB: d1u3wa2, d1u3wb2
   complexed with fxy, nad, zn

Details for d1u3wb1

PDB Entry: 1u3w, 1.45 Å

PDB Description: crystal structure of human alcohol dehydrogenase gamma-2-gamma-2 isoform complexed with n-1-methylheptylformamide determined to 1.45 angstrom resolution

PDB Compounds: (B:) Alcohol dehydrogenase gamma chain

SCOP Domain Sequences for d1u3wb1:

Sequence; same for both SEQRES and ATOM records:

>d1u3wb1 b.35.1.2 (B:1-162,B:339-374) Alcohol dehydrogenase {Human (Homo sapiens), different isozymes [TaxId: 9606]}
stagkvikckaavlwelkkpfsieevevappkahevrikmvaagicrsdehvvsgnlvtp
lpvilgheaagivesvgegvttvkpgdkviplftpqcgkcricknpesnyclkndlgnpr
gtlqdgtrrftcsgkpihhfvgvstfsqytvvdenavakidaXkfsldalitnvlpfeki
negfdllrsgksirtvltf

Timeline for d1u3wb1:

• d1u3wb1 first appeared in SCOP 1.71
  
• d1u3wb1 appears in SCOP 1.73
  
• d1u3wb1 appears in SCOPe 2.01
  
• d1u3wb1 appears in the current release, SCOPe 2.08