Lineage for d1rwv.1 (1rwv A:,B:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2854798Fold c.17: Caspase-like [52128] (1 superfamily)
    3 layers, a/b/a; core: mixed beta-sheet of 6 strands, order 213456, strand 6 is antiparallel to the rest
  4. 2854799Superfamily c.17.1: Caspase-like [52129] (3 families) (S)
    mature protein may be composed of two chains folded in a single domain
  5. 2854800Family c.17.1.1: Caspase catalytic domain [52130] (8 proteins)
  6. 2854910Protein Interleukin-1beta converting enzyme (a cysteine protease) [52133] (1 species)
  7. 2854911Species Human (Homo sapiens) [TaxId:9606] [52134] (14 PDB entries)
    Uniprot P29466 125-297,317-404
  8. 2854916Domain d1rwv.1: 1rwv A:,B: [111956]
    complexed with 5ph

Details for d1rwv.1

PDB Entry: 1rwv (more details), 2.1 Å

PDB Description: Crystal structure of human caspase-1 in complex with 5-[5-(1-carboxymethyl-2-oxo-propylcarbamoyl)-5-phenyl-pentylsulfamoyl]-2-hydroxy-benzoic acid
PDB Compounds: (A:) Interleukin-1 beta convertase, (B:) Interleukin-1 beta convertase

SCOPe Domain Sequences for d1rwv.1:

Sequence; same for both SEQRES and ATOM records: (download)

>g1rwv.1 c.17.1.1 (A:,B:) Interleukin-1beta converting enzyme (a cysteine protease) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d1rwv.1:

Click to download the PDB-style file with coordinates for d1rwv.1.
(The format of our PDB-style files is described here.)

Timeline for d1rwv.1: