SCOPe 2.08: Domain d1rtka1: 1rtk A:453-739

Lineage for d1rtka1 (1rtk A:453-739)

1. Root: SCOPe 2.08

2. Class b: All beta proteins [48724] (180 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Factor B [50561] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50562] (4 PDB entries)
   Uniprot P00751 268-764

8. Domain d1rtka1: 1rtk A:453-739 [111932]
   Other proteins in same PDB: d1rtka2
   complexed with gbs, iod, mg, na

Details for d1rtka1

PDB Entry: 1rtk, 2.3 Å

PDB Description: crystal structure analysis of the bb segment of factor b complexed with 4-guanidinobenzoic acid

PDB Compounds: (A:) complement factor b

SCOPe Domain Sequences for d1rtka1:

Sequence, based on SEQRES records:

>d1rtka1 b.47.1.2 (A:453-739) Factor B {Human (Homo sapiens) [TaxId: 9606]}
cgmvwehrkgtdyhkqpwqakisvirpskghescmgavvseyfvltaahcftvddkehsi
kvsvggekrdleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpicl
pctegttralrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgsce
rdaqyapgydkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgvi
swgvvdvcknqkrqkqvpahardfhinlfqvlpwlkeklqdedlgfl

Sequence, based on observed residues (ATOM records):

>d1rtka1 b.47.1.2 (A:453-739) Factor B {Human (Homo sapiens) [TaxId: 9606]}
cgmvwehrkgtdyhkqpwqakisvirkghescmgavvseyfvltaahcftvddkehsikv
svggekrdleievvlfhpnyningkkeagipefydydvaliklknklkygqtirpiclpc
tegttralrlpptttcqqqkeellpaqdikalfvseeekkltrkevyikngdkkgscerd
aqyapgydkvkdisevvtprflctggvspyadpntcrgdsggplivhkrsrfiqvgvisw
gvvdvckrqkqvpahardfhinlfqvlpwlkeklqdedlgfl

Timeline for d1rtka1:

• d1rtka1 first appeared in SCOP 1.71
  
• d1rtka1 appears in SCOPe 2.07