SCOPe 2.08: Domain d1w2fb_: 1w2f B:

Lineage for d1w2fb_ (1w2f B:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.143: SAICAR synthase-like [56103] (1 superfamily)
   consists of two alpha+beta subdomains

4. Superfamily d.143.1: SAICAR synthase-like [56104] (4 families)
   shares functional and structural similarities with the ATP-grasp fold and protein kinase superfamilies

5. Family d.143.1.3: Inositol polyphosphate kinase (IPK) [111188] (2 proteins)
   Pfam PF03770

6. Protein Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A [111189] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [111190] (3 PDB entries)
   Uniprot P23677 187-461

8. Domain d1w2fb_: 1w2f B: [109126]
   complexed with so4

Details for d1w2fb_

PDB Entry: 1w2f, 1.8 Å

PDB Description: human inositol (1,4,5)-trisphosphate 3-kinase substituted with selenomethionine

PDB Compounds: (B:) inositol-trisphosphate 3-kinase a

SCOPe Domain Sequences for d1w2fb_:

Sequence, based on SEQRES records:

>d1w2fb_ d.143.1.3 (B:) Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A {Human (Homo sapiens) [TaxId: 9606]}
mswvqlaghtgsfkaagtsglilkrcseperyclarlmadalrgcvpafhgvverdgesy
lqlqdlldgfdgpcvldckmgvrtyleeeltkarerpklrkdmykkmlavdpeapteeeh
aqravtkprymqwregisssttlgfriegikkadgscstdfkttrsreqvlrvfeefvqg
deevlrrylnrlqqirdtlevseffrrhevigssllfvhdhchragvwlidfgkttplpd
gqildhrrpweegnredgyllgldnligilaslaer

Sequence, based on observed residues (ATOM records):

>d1w2fb_ d.143.1.3 (B:) Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A {Human (Homo sapiens) [TaxId: 9606]}
mswvqlasfkaagtsglilkrcseperyclarlmadalrgcvpafhgvverdgesylqlq
dlldgfdgpcvldckmgvrtyleeeltkarerpklrkdmykkmlavdpeapteeehaqra
vtkprymqwregisssttlgfriegikkadgscstdfkttrsreqvlrvfeefvqgdeev
lrrylnrlqqirdtlevseffrrhevigssllfvhdhchragvwlidfgkttplpdgqil
dhrrpweegnredgyllgldnligilaslaer

Timeline for d1w2fb_:

• d1w2fb_ first appeared in SCOP 1.69
  
• d1w2fb_ appears in SCOPe 2.07