SCOP 1.71: Domain d1tzdb_: 1tzd B:

Lineage for d1tzdb_ (1tzd B:)

1. Root: SCOP 1.71

2. Class d: Alpha and beta proteins (a+b) [53931] (286 folds)

3. Fold d.143: SAICAR synthase-like [56103] (1 superfamily)
   consists of two alpha+beta subdomains

4. Superfamily d.143.1: SAICAR synthase-like [56104] (3 families)
   shares functional and structural similarities with the ATP-grasp fold and protein kinase superfamilies

5. Family d.143.1.3: Inositol polyphosphate kinase (IPK) [111188] (1 protein)
   Pfam 03770

6. Protein Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A [111189] (2 species)

7. Species Rat (Rattus norvegicus) [TaxId:10116] [111191] (1 PDB entry)

8. Domain d1tzdb_: 1tzd B: [107475]
   complexed with adp, mg

Details for d1tzdb_

PDB Entry: 1tzd, 2.2 Å

PDB Description: crystal structure of the catalytic core of inositol 1,4,5- trisphosphate 3-kinase

SCOP Domain Sequences for d1tzdb_:

Sequence, based on SEQRES records:

>d1tzdb_ d.143.1.3 (B:) Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A {Rat (Rattus norvegicus)}
glilkrssepehycmvrlmadvlrgcvpafhgvverdgesylqlqdlldgfdgpcvldck
mgvrtyleeeltkarerpklrkdmykkmlavdpeapteeehaqravtkprymqwregiss
sttlgfriegikkadgscstdfkttrsreqvtrvfeefmqgdaevlkrylnrlqqirdtl
eisdffrrhevigssllfvhdhchragvwlidfgkttplpngqildhrrpweegnredgy
llgldnligilanla

Sequence, based on observed residues (ATOM records):

>d1tzdb_ d.143.1.3 (B:) Inositol 1,4,5-trisphosphate 3-kinase A, IP3K A {Rat (Rattus norvegicus)}
glilkrssepehycmvrlmadvlrgcvpafhgvvlqlqdlldgfdgpcvldckmgvrtyl
eeeltkarerpklrkdmykkmlavdpeapteeehaprymqwregisssttlgfriegikk
adgscstdfkttrsreqvtrvfeefmqgdaevlkrylnrlqqirdtleisdffrrhevig
ssllfvhdhchragvwlidfgkttplpngqildhrrpweegnredgyllgldnligilan
la

Timeline for d1tzdb_:

• d1tzdb_ first appeared in SCOP 1.69
  
• d1tzdb_ appears in SCOP 1.73
  
• d1tzdb_ appears in the current release, SCOPe 2.08