SCOPe 2.01: Domain d1tbwa_: 1tbw A:

Lineage for d1tbwa_ (1tbw A:)

1. Root: SCOPe 2.01

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (4 families)

5. Family d.122.1.1: Heat shock protein 90, HSP90, N-terminal domain [55875] (2 proteins)

6. Protein HSP90 [55876] (3 species)

7. Species Dog (Canis familiaris) [TaxId:9615] [103225] (22 PDB entries)
   Uniprot P41148 76-285; Endoplasmin, GRP94

8. Domain d1tbwa_: 1tbw A: [106746]
   complexed with amp, mg, pg4

Details for d1tbwa_

PDB Entry: 1tbw, 2.15 Å

PDB Description: ligand induced conformational shift in the n-terminal domain of grp94, open conformation

PDB Compounds: (A:) Endoplasmin

SCOPe Domain Sequences for d1tbwa_:

Sequence, based on SEQRES records:

>d1tbwa_ d.122.1.1 (A:) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
fafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneeltvk
ikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqedgqstseligqf
gvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlkeea
sdyleldtiknlvkkysqfinfpiyvwssktggggktvwdwelmn

Sequence, based on observed residues (ATOM records):

>d1tbwa_ d.122.1.1 (A:) HSP90 {Dog (Canis familiaris) [TaxId: 9615]}
fafqaevnrmmkliinslyknkeiflrelisnasdaldkirlisltdenalagneeltvk
ikcdkeknllhvtdtgvgmtreelvknlgtiaksgtseflnkmteaqedgqstseligqf
gvgfysaflvadkvivtskhnndtqhiwesdsnefsviadprgntlgrgttitlvlkeea
sdyleldtiknlvkkysqfinfpiyvwssktgktvwdwelmn

Timeline for d1tbwa_:

• d1tbwa_ first appeared in SCOP 1.69
  
• d1tbwa_ appears in SCOP 1.75
  
• d1tbwa_ appears in SCOPe 2.02
  
• d1tbwa_ appears in the current release, SCOPe 2.08