SCOPe 2.06: Domain d1t9sb_: 1t9s B:

Lineage for d1t9sb_ (1t9s B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.2: PDEase [48548] (7 proteins)
   Pfam PF00233; multihelical; can be divided into three subdomains

6. Protein cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx [101439] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [101440] (19 PDB entries)
   Uniprot O76074 534-860

8. Domain d1t9sb_: 1t9s B: [106727]
   complexed with 5gp, mg, zn

Details for d1t9sb_

PDB Entry: 1t9s, 2 Å

PDB Description: catalytic domain of human phosphodiesterase 5a in complex with gmp

PDB Compounds: (B:) cGMP-specific 3',5'-cyclic phosphodiesterase

SCOPe Domain Sequences for d1t9sb_:

Sequence; same for both SEQRES and ATOM records:

>d1t9sb_ a.211.1.2 (B:) cGMP-specific 3',5'-cyclic phosphodiesterase pde5a1-Ibmx {Human (Homo sapiens) [TaxId: 9606]}
eeetrelqslaaavvpsaqtlkitdfsfsdfelsdletalctirmftdlnlvqnfqmkhe
vlcrwilsvkknyrknvayhnwrhafntaqcmfaalkagkiqnkltdleilalliaalsh
dldhpgvsnqflintnselalmyndesvlehhhfdqclmilnspgnqilsglsieeyktt
lkiikqailatdlalyikrrgeffelirknqfnledphqkelflamlmtacdlsaitkpw
piqqriaelvateffdqgdrerkelnieptdlmnrekknkipsmqvgfidaiclqlyeal
thvsedcfplldgcrknrqkwqalae

Timeline for d1t9sb_:

• d1t9sb_ first appeared in SCOP 1.69
  
• d1t9sb_ appears in SCOPe 2.05
  
• d1t9sb_ appears in SCOPe 2.07
  
• d1t9sb_ appears in the current release, SCOPe 2.08