SCOP 1.71: Domain d1rv4b_: 1rv4 B:

Lineage for d1rv4b_ (1rv4 B:)

1. Root: SCOP 1.71

2. Class c: Alpha and beta proteins (a/b) [51349] (134 folds)

3. Fold c.67: PLP-dependent transferases [53382] (1 superfamily)
   main domain: 3 layers: a/b/a, mixed beta-sheet of 7 strands, order 3245671; strand 7 is antiparallel to the rest

4. Superfamily c.67.1: PLP-dependent transferases [53383] (6 families)

5. Family c.67.1.4: GABA-aminotransferase-like [53417] (13 proteins)
   formerly omega-Aminoacid:pyruvate aminotransferase-like

6. Protein Serine hydroxymethyltransferase [53429] (5 species)

7. Species Rabbit (Oryctolagus cuniculus) [TaxId:9986] [53430] (6 PDB entries)

8. Domain d1rv4b_: 1rv4 B: [105104]
   complexed with plp, po4; mutant

Details for d1rv4b_

PDB Entry: 1rv4, 2.95 Å

PDB Description: e75l mutant of rabbit cytosolic serine hydroxymethyltransferase

SCOP Domain Sequences for d1rv4b_:

Sequence, based on SEQRES records:

>d1rv4b_ c.67.1.4 (B:) Serine hydroxymethyltransferase {Rabbit (Oryctolagus cuniculus)}
wssheqmlaqplkdsdaevydiikkesnrqrvgleliasenfasravlealgsclnnkys
lgypgqryyggtehideletlcqkralqaygldpqcwgvnvqpysgspanfavytalvep
hgrimgldlpdgghlthgfmtdkkkisatsiffesmaykvnpdtgyidydrleenarlfh
pkliiagtscysrnldygrlrkiadengaylmadmahisglvvagvvpspfehchvvttt
thktlrgcragmifyrrgvrsvdpktgkeilynleslinsavfpglqggphnhaiagvav
alkqamtpefkeyqrqvvancralsaalvelgykivtggsdnhlilvdlrskgtdggrae
kvleacsiacnkntcpgdksalrpsglrlgtpaltsrgllekdfqkvahfihrgieltvq
iqddtgpratlkefkeklagdekhqravralrqevesfaalfplpglpgf

Sequence, based on observed residues (ATOM records):

>d1rv4b_ c.67.1.4 (B:) Serine hydroxymethyltransferase {Rabbit (Oryctolagus cuniculus)}
wssheqmlaqplkdsdaevydiikkesnrqrvgleliasenfasravlealgsclnnkys
lgypgqryyggtehideletlcqkralqaygldpqcwgvnvqpysgspanfavytalvep
hgrimgldlpdgghlthgfmtdkkkisatsiffesmaykvnpdtgyidydrleenarlfh
pkliiagtscysrnldygrlrkiadengaylmadmahisglvvagvvpspfehchvvttt
thktlrgcragmifyrrgvrsvdkeilynleslinsavfpglqggphnhaiagvavalkq
amtpefkeyqrqvvancralsaalvelgykivtggsdnhlilvdlrskgtdggraekvle
acsiacnkntcpgdksalrpsglrlgtpaltsrgllekdfqkvahfihrgieltvqiqdd
tgpratlkefkeklagdekhqravralrqevesfaalfplpglpgf

Timeline for d1rv4b_:

• d1rv4b_ first appeared in SCOP 1.69
  
• d1rv4b_ appears in SCOP 1.73
  
• d1rv4b_ appears in the current release, SCOPe 2.08