SCOP 1.71: Domain d1r9oa_: 1r9o A:

Lineage for d1r9oa_ (1r9o A:)

1. Root: SCOP 1.71

2. Class a: All alpha proteins [46456] (226 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (1 family)

5. Family a.104.1.1: Cytochrome P450 [48265] (21 proteins)

6. Protein Mammalian cytochrome p450 2c9 [89118] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89119] (3 PDB entries)

8. Domain d1r9oa_: 1r9o A: [104878]
   complexed with flp, gol, hem; mutant

Details for d1r9oa_

PDB Entry: 1r9o, 2 Å

PDB Description: crystal structure of p4502c9 with flurbiprofen bound

SCOP Domain Sequences for d1r9oa_:

Sequence, based on SEQRES records:

>d1r9oa_ a.104.1.1 (A:) Mammalian cytochrome p450 2c9 {Human (Homo sapiens)}
rgklppgptplpvignilqigikdisksltnlskvygpvftlyfglkpivvlhgyeavke
alidlgeefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkrsiedrv
qeearclveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlmeklneni
kilsspwiqicnnfspiidyfpgthnkllknvafmksyilekvkehqesmdmnnpqdfid
cflmkmekekhnqpseftieslentavdlfgagtettsttlryalllllkhpevtakvqe
eiervigrnrspcmqdrshmpytdavvhevqryidllptslphavtcdikfrnylipkgt
tilisltsvlhdnkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgealagmel
flfltsilqnfnlkslvdpknldttpvvngfasvppfyqlcfipihh

Sequence, based on observed residues (ATOM records):

>d1r9oa_ a.104.1.1 (A:) Mammalian cytochrome p450 2c9 {Human (Homo sapiens)}
rgklppgptplplqigikdisksltnlskvygpvftlyfglkpivvlhgyeavkealidl
geefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkrsiedrvqeear
clveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlmeklnenikilss
pwipiidyfpgthnkllknvafmksyilekvkehqesmdmnnpqdfidcflmkmekekhn
qpseftieslentavdlfgagtettsttlryalllllkhpevtakvqeeiervigrnrsp
cmqdrshmpytdavvhevqryidllptslphavtcdikfrnylipkgttilisltsvlhd
nkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgealagmelflfltsilqnfn
lkslvdpknldttpvvngfasvppfyqlcfipihh

Timeline for d1r9oa_:

• d1r9oa_ first appeared in SCOP 1.69
  
• d1r9oa_ appears in SCOP 1.73
  
• d1r9oa_ appears in the current release, SCOPe 2.08, called d1r9oa1