SCOPe 2.08: Domain d1r9oa1: 1r9o A:26-490

Lineage for d1r9oa1 (1r9o A:26-490)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.104: Cytochrome P450 [48263] (1 superfamily)
   multihelical

4. Superfamily a.104.1: Cytochrome P450 [48264] (2 families)

5. Family a.104.1.1: Cytochrome P450 [48265] (23 proteins)

6. Protein Mammalian cytochrome p450 2c9 [89118] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [89119] (4 PDB entries)
   Uniprot P11712

8. Domain d1r9oa1: 1r9o A:26-490 [104878]
   Other proteins in same PDB: d1r9oa2
   complexed with flp, gol, hem

Details for d1r9oa1

PDB Entry: 1r9o, 2 Å

PDB Description: crystal structure of p4502c9 with flurbiprofen bound

PDB Compounds: (A:) Cytochrome P450 2C9

SCOPe Domain Sequences for d1r9oa1:

Sequence, based on SEQRES records:

>d1r9oa1 a.104.1.1 (A:26-490) Mammalian cytochrome p450 2c9 {Human (Homo sapiens) [TaxId: 9606]}
rgklppgptplpvignilqigikdisksltnlskvygpvftlyfglkpivvlhgyeavke
alidlgeefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkrsiedrv
qeearclveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlmeklneni
kilsspwiqicnnfspiidyfpgthnkllknvafmksyilekvkehqesmdmnnpqdfid
cflmkmekekhnqpseftieslentavdlfgagtettsttlryalllllkhpevtakvqe
eiervigrnrspcmqdrshmpytdavvhevqryidllptslphavtcdikfrnylipkgt
tilisltsvlhdnkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgealagmel
flfltsilqnfnlkslvdpknldttpvvngfasvppfyqlcfipi

Sequence, based on observed residues (ATOM records):

>d1r9oa1 a.104.1.1 (A:26-490) Mammalian cytochrome p450 2c9 {Human (Homo sapiens) [TaxId: 9606]}
rgklppgptplplqigikdisksltnlskvygpvftlyfglkpivvlhgyeavkealidl
geefsgrgifplaeranrgfgivfsngkkwkeirrfslmtlrnfgmgkrsiedrvqeear
clveelrktkaspcdptfilgcapcnvicsiifhkrfdykdqqflnlmeklnenikilss
pwipiidyfpgthnkllknvafmksyilekvkehqesmdmnnpqdfidcflmkmekekhn
qpseftieslentavdlfgagtettsttlryalllllkhpevtakvqeeiervigrnrsp
cmqdrshmpytdavvhevqryidllptslphavtcdikfrnylipkgttilisltsvlhd
nkefpnpemfdphhfldeggnfkkskyfmpfsagkricvgealagmelflfltsilqnfn
lkslvdpknldttpvvngfasvppfyqlcfipi

Timeline for d1r9oa1:

• d1r9oa1 first appeared in SCOP 1.69, called d1r9oa_
  
• d1r9oa1 appears in SCOPe 2.07