SCOPe 2.08: Protein: Protein FkbI

Root: SCOPe 2.08
Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)
Fold e.6: Acyl-CoA dehydrogenase NM domain-like [56644] (1 superfamily)
2 domains: (1) all-alpha: 5 helices; (2) contains an open beta-sheet barrel: n*=5, S*=8; complex topology
Superfamily e.6.1: Acyl-CoA dehydrogenase NM domain-like [56645] (3 families)
flavoprotein: binds FAD; constituent families differ in the numbers of C-terminal domains (four-helical bundles)
Family e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains [56646] (10 proteins)
Protein Protein FkbI [103396] (1 species)
involved in biosynthesis of methoxymalonyl extender unit of fk520 polyketide immunosuppressant

Streptomyces hygroscopicus [TaxId:1912] [103397] (1 PDB entry)
- Domain for 1r2j:
  - Domain d1r2ja2: 1r2j A:3-212 [96870]
    Other proteins in same PDB: d1r2ja1
    complexed with fad

Timeline for Protein Protein FkbI from e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains:

Protein Protein FkbI from e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains first appeared in SCOP 1.67
Protein Protein FkbI from e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains appears in SCOPe 2.07