Lineage for Family e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains

  1. Root: SCOPe 2.08
  2. Class e: Multi-domain proteins (alpha and beta) [56572] (74 folds)
  3. Fold e.6: Acyl-CoA dehydrogenase NM domain-like [56644] (1 superfamily)
    2 domains: (1) all-alpha: 5 helices; (2) contains an open beta-sheet barrel: n*=5, S*=8; complex topology
  4. Superfamily e.6.1: Acyl-CoA dehydrogenase NM domain-like [56645] (3 families) (S)
    flavoprotein: binds FAD; constituent families differ in the numbers of C-terminal domains (four-helical bundles)
  5. Family e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains [56646] (10 proteins)

Proteins:

  1. 4-hydroxybutyryl-CoA dehydratase AbfD, NM domains [118187] (1 species)
  2. Acyl-CoA dehydrogenase [144024] (1 species)
  3. Butyryl-CoA dehydrogenase, NM domains [56647] (2 species)
    1. Species Megasphaera elsdenii [TaxId:907] [56648] (1 PDB entry)
    2. Species Norway rat (Rattus norvegicus) [TaxId:10116] [69877] (1 PDB entry)
  4. Glutaryl-CoA dehydrogenase GCDH [111293] (1 species)
  5. Isobutyryl-CoA dehydrogenase [103394] (1 species)
  6. Isovaleryl-coa dehydrogenase, NM domains [56652] (1 species)
  7. Medium chain acyl-CoA dehydrogenase, NM domains [56649] (3 species)
    1. Species Human (Homo sapiens) [TaxId:9606] [56651] (5 PDB entries)
      Uniprot P11310 34-421
    2. Species Pig (Sus scrofa) [TaxId:9823] [56650] (3 PDB entries)
    3. Species Thermus thermophilus [TaxId:274] [118186] (1 PDB entry)
      Uniprot Q5SJ70 32-409
  8. Nitroalkane oxidase [144026] (1 species)
  9. Protein FkbI [103396] (1 species)
    involved in biosynthesis of methoxymalonyl extender unit of fk520 polyketide immunosuppressant
  10. automated matches [226961] (2 species)
    not a true protein
    1. Species Fungus (Fusarium oxysporum) [TaxId:5507] [231929] (7 PDB entries)
    2. Species Human (Homo sapiens) [TaxId:9606] [225392] (3 PDB entries)

More info for Family e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains

Timeline for Family e.6.1.1: Medium chain acyl-CoA dehydrogenase, NM (N-terminal and middle) domains: