SCOP 1.75: Domain d1v0pb_: 1v0p B:

Lineage for d1v0pb_ (1v0p B:)

1. Root: SCOP 1.75

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (7 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (63 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Cyclin-dependent PK, CDK2 [88855] (2 species)
   CMGC group; CDKs subfamily; serine/threonine kinase

7. Species (Plasmodium falciparum) [TaxId:5833] [103289] (4 PDB entries)
   CDK2 homologue Pfpk5

8. Domain d1v0pb_: 1v0p B: [100246]
   complexed with pvb; mutant

Details for d1v0pb_

PDB Entry: 1v0p, 2 Å

PDB Description: structure of p. falciparum pfpk5-purvalanol b ligand complex

PDB Compounds: (B:) cell division control protein 2 homolog

SCOP Domain Sequences for d1v0pb_:

Sequence, based on SEQRES records:

>d1v0pb_ d.144.1.7 (B:) Cyclin-dependent PK, CDK2 {(Plasmodium falciparum) [TaxId: 5833]}
ekyhglekigegtygvvykaqnnygetfalkkirlekedegipsttireisilkelkhsn
ivklydvihtkkrlvlvfehldqdlkklldvcegglesvtaksfllqllngiaychdrrv
lhrdlkpqnllinregelkiadfglarafgipvrkytheivtlwyrapdvlmgskkystt
idiwsvgcifaemvngtplfpgvseadqlmrifrilgtpnsknwpnvtelpkydpnftvy
eplpwesflkgldesgidllskmlkldpnqritakqalehayfke

Sequence, based on observed residues (ATOM records):

>d1v0pb_ d.144.1.7 (B:) Cyclin-dependent PK, CDK2 {(Plasmodium falciparum) [TaxId: 5833]}
ekyhglekigegtygvvykaqnnygetfalkpsttireisilkelkhsnivklydvihtl
vlvfehldqdlkklldvcegglesvtaksfllqllngiaychdrrvlhrdlkpqnllinr
egelkiadfglaraflwyrapdvlmgskkysttidiwsvgcifaemvngtplfpgvsead
qlmrifrilgtpnsknwpnvtelpkydpnftvyeplpwesflkgldesgidllskmlkld
pnqritakqalehayfke

Timeline for d1v0pb_:

• d1v0pb_ first appeared in SCOP 1.67
  
• d1v0pb_ appears in SCOP 1.73
  
• d1v0pb_ appears in SCOPe 2.01
  
• d1v0pb_ appears in the current release, SCOPe 2.08