Class c: Alpha and beta proteins (a/b) [51349] (148 folds) |
Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies) contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678 the first seven superfamilies have similar phosphate-binding sites |
Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families) |
Family c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like [88704] (4 proteins) forms a swapped dimer |
Protein Isocitrate lyase [51642] (5 species) elaborated with additional subdomains |
Species Escherichia coli [TaxId:562] [63923] (1 PDB entry) |
Domain d1igwa_: 1igw A: [62370] complexed with hg, mg, pyr; mutant has additional subdomain(s) that are not in the common domain |
PDB Entry: 1igw (more details), 2.1 Å
SCOPe Domain Sequences for d1igwa_:
Sequence, based on SEQRES records: (download)
>d1igwa_ c.1.12.7 (A:) Isocitrate lyase {Escherichia coli [TaxId: 562]} ktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhges kkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpavv erinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieagaa avhfedqlasvkkcghmggkvlvptqeaiqklvaarlcadvtgvptllvartdadaadli tsdcdpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarrf aqaihakypgkllayncspsfnwqknlddktiasfqqqlsdmgykfqfitlagihsmwfn mfdlanayaqgegmkhyvekvqqpefaaakdgytfvshqqevgtgyfdkvttiiqg
>d1igwa_ c.1.12.7 (A:) Isocitrate lyase {Escherichia coli [TaxId: 562]} ktrtqqieelqkewtqprwegitrpysaedvvklrgsvnpectlaqlgaakmwrllhges kkgyinslgaltggqalqqakagieavylsgwqvaadanlaasmypdqslypansvpavv erinntfrradqiqwsagiepgdpryvdyflpivadaeagfggvlnafelmkamieagaa avhfedqlasvkkcgkvlvptqeaiqklvaarlcadvtgvptllvartdadaadlitsdc dpydsefitgertsegffrthagieqaisrglayapyadlvwcetstpdlelarrfaqai hakypgkllayncsfqqqlsdmgykfqfitlagihsmwfnmfdlanayaqgegmkhyvek vqqpefaaakdgytfvshqqevgtgyfdkvttiiqg
Timeline for d1igwa_: