Lineage for Protein: Isocitrate lyase

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2078560Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2088020Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families) (S)
  5. 2088212Family c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like [88704] (4 protein domains)
    forms a swapped dimer
  6. 2088236Protein Isocitrate lyase [51642] (4 species)
    elaborated with additional subdomains

Species:

  1. 2088237Emericella nidulans (Aspergillus nidulans) [TaxId:162425] [51643] (1 PDB entry)
  2. 2088239Escherichia coli [TaxId:562] [63923] (1 PDB entry)
  3. 2088244Mycobacterium tuberculosis [TaxId:1773] [51644] (3 PDB entries)
    1. Domains for 1f61:
      1. 2088249Domain d1f61a_: 1f61 A: [29319]
        complexed with mg
      2. 2088250Domain d1f61b_: 1f61 B: [29320]
        complexed with mg
    2. Domains for 1f8i:
      1. 2088251Domain d1f8ia_: 1f8i A: [29321]
        complexed with glv, mg, sin
      2. 2088252Domain d1f8ib_: 1f8i B: [29322]
        complexed with glv, mg, sin
      3. 2088253Domain d1f8ic_: 1f8i C: [29323]
        complexed with glv, mg, sin
      4. 2088254Domain d1f8id_: 1f8i D: [29324]
        complexed with glv, mg, sin
    3. Domains for 1f8m:
      1. 2088245Domain d1f8ma_: 1f8m A: [29315]
        complexed with mg, pyr
      2. 2088246Domain d1f8mb_: 1f8m B: [29316]
        complexed with mg, pyr
      3. 2088247Domain d1f8mc_: 1f8m C: [29317]
        complexed with mg, pyr
      4. 2088248Domain d1f8md_: 1f8m D: [29318]
        complexed with mg, pyr
  4. 2279176Mycobacterium tuberculosis [TaxId:652616] [322477] (1 PDB entry)

More info for Protein Isocitrate lyase from c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like

Timeline for Protein Isocitrate lyase from c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like: