Lineage for Protein: Isocitrate lyase

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2413227Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2423593Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families) (S)
  5. 2423788Family c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like [88704] (4 protein domains)
    forms a swapped dimer
  6. 2423812Protein Isocitrate lyase [51642] (4 species)
    elaborated with additional subdomains

Species:

  1. 2423813Emericella nidulans (Aspergillus nidulans) [TaxId:162425] [51643] (1 PDB entry)
  2. 2423815Escherichia coli [TaxId:562] [63923] (1 PDB entry)
  3. 2423820Mycobacterium tuberculosis [TaxId:1773] [51644] (3 PDB entries)
    1. Domains for 1f61:
      1. 2423825Domain d1f61a_: 1f61 A: [29319]
        complexed with mg
      2. 2423826Domain d1f61b_: 1f61 B: [29320]
        complexed with mg
    2. Domains for 1f8i:
      1. 2423827Domain d1f8ia_: 1f8i A: [29321]
        complexed with glv, mg, sin
      2. 2423828Domain d1f8ib_: 1f8i B: [29322]
        complexed with glv, mg, sin
      3. 2423829Domain d1f8ic_: 1f8i C: [29323]
        complexed with glv, mg, sin
      4. 2423830Domain d1f8id_: 1f8i D: [29324]
        complexed with glv, mg, sin
    3. Domains for 1f8m:
      1. 2423821Domain d1f8ma_: 1f8m A: [29315]
        complexed with mg, pyr
      2. 2423822Domain d1f8mb_: 1f8m B: [29316]
        complexed with mg, pyr
      3. 2423823Domain d1f8mc_: 1f8m C: [29317]
        complexed with mg, pyr
      4. 2423824Domain d1f8md_: 1f8m D: [29318]
        complexed with mg, pyr
  4. 2423831Mycobacterium tuberculosis [TaxId:652616] [322477] (3 PDB entries)
    1. Domains for 5dql:
      1. 2423832Domain d5dqla_: 5dql A: [322579]
        automated match to d1f8ia_
        complexed with mg, vgx
      2. 2423833Domain d5dqlb_: 5dql B: [322478]
        automated match to d1f8ia_
        complexed with mg, vgx
      3. 2423834Domain d5dqlc_: 5dql C: [322544]
        automated match to d1f8ia_
        complexed with mg, vgx
      4. 2423835Domain d5dqld_: 5dql D: [322507]
        automated match to d1f8ia_
        complexed with mg, vgx
    2. Domains for 6c4a:
      1. 3053106Domain d6c4ad_: 6c4a D: [353168]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr
      2. 3053110Domain d6c4ag_: 6c4a G: [353172]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr
      3. 3053118Domain d6c4af_: 6c4a F: [353180]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr
      4. 3053142Domain d6c4ab_: 6c4a B: [353204]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr
      5. 3053164Domain d6c4ah_: 6c4a H: [353226]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr
      6. 3053213Domain d6c4aa1: 6c4a A:1-427 [353275]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr
      7. 3053306Domain d6c4ac_: 6c4a C: [353368]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr
      8. 3053333Domain d6c4ae_: 6c4a E: [353395]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr
    3. Domains for 6c4c:
      1. 3053107Domain d6c4cc_: 6c4c C: [353169]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr
      2. 3053108Domain d6c4ch_: 6c4c H: [353170]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr
      3. 3053109Domain d6c4ce_: 6c4c E: [353171]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr
      4. 3053205Domain d6c4ca1: 6c4c A:1-427 [353267]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr
      5. 3053225Domain d6c4cd_: 6c4c D: [353287]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr
      6. 3053258Domain d6c4cf_: 6c4c F: [353320]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr
      7. 3053322Domain d6c4cg_: 6c4c G: [353384]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr
      8. 3053326Domain d6c4cb_: 6c4c B: [353388]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr

More info for Protein Isocitrate lyase from c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like

Timeline for Protein Isocitrate lyase from c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like: