Lineage for Protein: Isocitrate lyase

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2826025Fold c.1: TIM beta/alpha-barrel [51350] (34 superfamilies)
    contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
    the first seven superfamilies have similar phosphate-binding sites
  4. 2837913Superfamily c.1.12: Phosphoenolpyruvate/pyruvate domain [51621] (8 families) (S)
  5. 2838112Family c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like [88704] (4 proteins)
    forms a swapped dimer
  6. 2838136Protein Isocitrate lyase [51642] (5 species)
    elaborated with additional subdomains

Species:

  1. 2838137Emericella nidulans (Aspergillus nidulans) [TaxId:162425] [51643] (1 PDB entry)
    • Domain for 1dqu:
      • 2838138Domain d1dqua_: 1dqu A: [29314]
        has additional subdomain(s) that are not in the common domain
  2. 2838139Escherichia coli [TaxId:562] [63923] (1 PDB entry)
    • Domains for 1igw:
      1. 2838140Domain d1igwa_: 1igw A: [62370]
        complexed with hg, mg, pyr; mutant
        has additional subdomain(s) that are not in the common domain
      2. 2838141Domain d1igwb_: 1igw B: [62371]
        complexed with hg, mg, pyr; mutant
        has additional subdomain(s) that are not in the common domain
      3. 2838142Domain d1igwc_: 1igw C: [62372]
        complexed with hg, mg, pyr; mutant
        has additional subdomain(s) that are not in the common domain
      4. 2838143Domain d1igwd_: 1igw D: [62373]
        complexed with hg, mg, pyr; mutant
        has additional subdomain(s) that are not in the common domain
  3. 2838144Mycobacterium tuberculosis [TaxId:1773] [51644] (3 PDB entries)
    1. Domains for 1f61:
      1. 2838149Domain d1f61a_: 1f61 A: [29319]
        complexed with mg
        has additional subdomain(s) that are not in the common domain
      2. 2838150Domain d1f61b_: 1f61 B: [29320]
        complexed with mg
        has additional subdomain(s) that are not in the common domain
    2. Domains for 1f8i:
      1. 2838151Domain d1f8ia_: 1f8i A: [29321]
        complexed with glv, mg, sin
        has additional subdomain(s) that are not in the common domain
      2. 2838152Domain d1f8ib_: 1f8i B: [29322]
        complexed with glv, mg, sin
        has additional subdomain(s) that are not in the common domain
      3. 2838153Domain d1f8ic_: 1f8i C: [29323]
        complexed with glv, mg, sin
        has additional subdomain(s) that are not in the common domain
      4. 2838154Domain d1f8id_: 1f8i D: [29324]
        complexed with glv, mg, sin
        has additional subdomain(s) that are not in the common domain
    3. Domains for 1f8m:
      1. 2838145Domain d1f8ma_: 1f8m A: [29315]
        complexed with mg, pyr
        has additional subdomain(s) that are not in the common domain
      2. 2838146Domain d1f8mb_: 1f8m B: [29316]
        complexed with mg, pyr
        has additional subdomain(s) that are not in the common domain
      3. 2838147Domain d1f8mc_: 1f8m C: [29317]
        complexed with mg, pyr
        has additional subdomain(s) that are not in the common domain
      4. 2838148Domain d1f8md_: 1f8m D: [29318]
        complexed with mg, pyr
        has additional subdomain(s) that are not in the common domain
  4. 2838155Mycobacterium tuberculosis [TaxId:652616] [322477] (5 PDB entries)
    1. Domains for 5dql:
      1. 2838164Domain d5dqla_: 5dql A: [322579]
        automated match to d1f8ia_
        complexed with mg, vgx

        has additional subdomain(s) that are not in the common domain
      2. 2838165Domain d5dqlb_: 5dql B: [322478]
        automated match to d1f8ia_
        complexed with mg, vgx

        has additional subdomain(s) that are not in the common domain
      3. 2838166Domain d5dqlc_: 5dql C: [322544]
        automated match to d1f8ia_
        complexed with mg, vgx

        has additional subdomain(s) that are not in the common domain
      4. 2838167Domain d5dqld_: 5dql D: [322507]
        automated match to d1f8ia_
        complexed with mg, vgx

        has additional subdomain(s) that are not in the common domain
    2. Domains for 6c4a:
      1. 2838168Domain d6c4aa1: 6c4a A:1-427 [353275]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr

        has additional subdomain(s) that are not in the common domain
      2. 2838169Domain d6c4ab_: 6c4a B: [353204]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr

        has additional subdomain(s) that are not in the common domain
      3. 2838170Domain d6c4ac_: 6c4a C: [353368]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr

        has additional subdomain(s) that are not in the common domain
      4. 2838171Domain d6c4ad_: 6c4a D: [353168]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr

        has additional subdomain(s) that are not in the common domain
      5. 2838172Domain d6c4ae_: 6c4a E: [353395]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr

        has additional subdomain(s) that are not in the common domain
      6. 2838173Domain d6c4af_: 6c4a F: [353180]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr

        has additional subdomain(s) that are not in the common domain
      7. 2838174Domain d6c4ag_: 6c4a G: [353172]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr

        has additional subdomain(s) that are not in the common domain
      8. 2838175Domain d6c4ah_: 6c4a H: [353226]
        Other proteins in same PDB: d6c4aa2
        automated match to d5dqla_
        complexed with 3np, epe, mg, peg, pyr

        has additional subdomain(s) that are not in the common domain
    3. Domains for 6c4c:
      1. 2838176Domain d6c4ca1: 6c4c A:1-427 [353267]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr

        has additional subdomain(s) that are not in the common domain
      2. 2838177Domain d6c4cb_: 6c4c B: [353388]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr

        has additional subdomain(s) that are not in the common domain
      3. 2838178Domain d6c4cc_: 6c4c C: [353169]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr

        has additional subdomain(s) that are not in the common domain
      4. 2838179Domain d6c4cd_: 6c4c D: [353287]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr

        has additional subdomain(s) that are not in the common domain
      5. 2838180Domain d6c4ce_: 6c4c E: [353171]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr

        has additional subdomain(s) that are not in the common domain
      6. 2838181Domain d6c4cf_: 6c4c F: [353320]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr

        has additional subdomain(s) that are not in the common domain
      7. 2838182Domain d6c4cg_: 6c4c G: [353384]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr

        has additional subdomain(s) that are not in the common domain
      8. 2838183Domain d6c4ch_: 6c4c H: [353170]
        Other proteins in same PDB: d6c4ca2
        automated match to d5dqla_
        complexed with 3np, glv, mg, pyr

        has additional subdomain(s) that are not in the common domain
    4. Domains for 6vb9:
      1. 2838160Domain d6vb9a_: 6vb9 A: [397835]
        automated match to d5dqla_
        complexed with acy, mg, oxd, peg, qva

        has additional subdomain(s) that are not in the common domain
      2. 2838161Domain d6vb9b_: 6vb9 B: [397902]
        automated match to d5dqla_
        complexed with acy, mg, oxd, peg, qva

        has additional subdomain(s) that are not in the common domain
      3. 2838162Domain d6vb9c_: 6vb9 C: [397836]
        automated match to d5dqla_
        complexed with acy, mg, oxd, peg, qva

        has additional subdomain(s) that are not in the common domain
      4. 2838163Domain d6vb9d_: 6vb9 D: [397838]
        automated match to d5dqla_
        complexed with acy, mg, oxd, peg, qva

        has additional subdomain(s) that are not in the common domain
    5. Domains for 6wsi:
      1. 2838156Domain d6wsia_: 6wsi A: [402727]
        automated match to d5dqla_
        complexed with glv, gol, mg, peg, u9s

        has additional subdomain(s) that are not in the common domain
      2. 2838157Domain d6wsib_: 6wsi B: [402832]
        automated match to d5dqla_
        complexed with glv, gol, mg, peg, u9s

        has additional subdomain(s) that are not in the common domain
      3. 2838158Domain d6wsic_: 6wsi C: [402722]
        automated match to d5dqla_
        complexed with glv, gol, mg, peg, u9s

        has additional subdomain(s) that are not in the common domain
      4. 2838159Domain d6wsid_: 6wsi D: [402728]
        automated match to d5dqla_
        complexed with glv, gol, mg, peg, u9s

        has additional subdomain(s) that are not in the common domain
  5. 2838184Mycobacterium tuberculosis [TaxId:83332] [393401] (2 PDB entries)
    1. Domains for 6xpp:
      1. 2838185Domain d6xppa_: 6xpp A: [393436]
        automated match to d5dqla_
        complexed with itn, mg

        has additional subdomain(s) that are not in the common domain
      2. 2838186Domain d6xppb_: 6xpp B: [393475]
        automated match to d5dqla_
        complexed with itn, mg

        has additional subdomain(s) that are not in the common domain
      3. 2838187Domain d6xppc_: 6xpp C: [393454]
        automated match to d5dqla_
        complexed with itn, mg

        has additional subdomain(s) that are not in the common domain
      4. 2838188Domain d6xppd_: 6xpp D: [393402]
        automated match to d5dqla_
        complexed with itn, mg

        has additional subdomain(s) that are not in the common domain
    2. Domains for 7cp1:
      1. 2838189Domain d7cp1a_: 7cp1 A: [404774]
        automated match to d5dqla_
        complexed with itn, mg, sin

        has additional subdomain(s) that are not in the common domain
      2. 2838190Domain d7cp1b_: 7cp1 B: [404784]
        automated match to d5dqla_
        complexed with itn, mg, sin

        has additional subdomain(s) that are not in the common domain

More info for Protein Isocitrate lyase from c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like

Timeline for Protein Isocitrate lyase from c.1.12.7: Phosphoenolpyruvate mutase/Isocitrate lyase-like: