SCOPe 2.04: Structural Classification of Proteins

PDB entry 8fab

View 8fab on RCSB PDB site
Description: crystal structure of the fab fragment from the human myeloma immunoglobulin igg hil at 1.8 angstroms resolution
Class: immunoglobulin
Keywords: immunoglobulin
Deposited on 1992-03-23, released 1993-10-31
The last revision prior to the SCOPe 2.04 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.173
AEROSPACI score: 0.51 (click here for full SPACI score report)

Chains and heterogens:

Chain 'A':
Compound: igg1-lambda hil fab (light chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PIR S25738
  - conflict (18)
  - conflict (23-25)
  - conflict (27-29)
  - conflict (32)
  - conflict (40-41)
  - conflict (44)
  - conflict (47-48)
  - conflict (50-51)
  - conflict (58)
  - conflict (62)
  - conflict (64)
  - conflict (67)
  - conflict (69)
  - conflict (76)
  - conflict (79)
  - conflict (91)
  - conflict (93-95)
  - conflict (154)
Domains in SCOPe 2.04: d8faba1, d8faba2
Chain 'B':
Compound: igg1-lambda hil fab (heavy chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- EMBL CAA75032 (1-End)
  - conflict (2)
  - conflict (5-6)
  - conflict (22)
  - conflict (49)
  - conflict (53)
  - conflict (56-57)
  - conflict (60)
  - conflict (76)
  - conflict (87)
  - conflict (98-102)
  - conflict (104-106)
  - conflict (114)
  - conflict (217)
Domains in SCOPe 2.04: d8fabb1, d8fabb2
Chain 'C':
Compound: igg1-lambda hil fab (light chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- PIR S25738
  - conflict (18)
  - conflict (23-25)
  - conflict (27-29)
  - conflict (32)
  - conflict (40-41)
  - conflict (44)
  - conflict (47-48)
  - conflict (50-51)
  - conflict (58)
  - conflict (62)
  - conflict (64)
  - conflict (67)
  - conflict (69)
  - conflict (76)
  - conflict (79)
  - conflict (91)
  - conflict (93-95)
  - conflict (154)
Domains in SCOPe 2.04: d8fabc1, d8fabc2
Chain 'D':
Compound: igg1-lambda hil fab (heavy chain)
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
- EMBL CAA75032 (1-End)
  - conflict (2)
  - conflict (5-6)
  - conflict (22)
  - conflict (49)
  - conflict (53)
  - conflict (56-57)
  - conflict (60)
  - conflict (76)
  - conflict (87)
  - conflict (98-102)
  - conflict (104-106)
  - conflict (114)
  - conflict (217)
Domains in SCOPe 2.04: d8fabd1, d8fabd2
Heterogens: HOH

PDB Chain Sequences:

Chain 'A':
Sequence, based on SEQRES records: (download)

>8fabA (A:)
syeltqppsvsvspgqtaritcsanalpnqyaywyqqkpgrapvmviykdtqrpsgipqr
fssstsgttvtltisgvqaedeadyycqawdnsasifgggtkltvlgqpkaapsvtlfpp
sseelqankatlvclisdfypgavtvawkadsspikagvetttpskqsnnkyaassylsl
tpeqwkshrsyscqvthegstvektvaptecs

Sequence, based on observed residues (ATOM records): (download)

>8fabA (A:)
eltqppsvsvspgqtaritcsanalpnqyaywyqqkpgrapvmviykdtqrpsgipqrfs
sstsgttvtltisgvqaedeadyycqawdnsasifgggtkltvlgqpkaapsvtlfppss
eelqankatlvclisdfypgavtvawkadsspikagvetttpskqsnnkyaassylsltp
eqwkshrsyscqvthegstvektvap

Chain 'B':
Sequence, based on SEQRES records: (download)

>8fabB (B:)
avklvqagggvvqpgrslrlsciasgftfsnygmhwvrqapgkglewvaviwyngsrtyy
gdsvkgrftisrdnskrtlymqmnslrtedtavyycardpdiltafsfdywgqgvlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

Sequence, based on observed residues (ATOM records): (download)

>8fabB (B:)
avklvqagggvvqpgrslrlsciasgftfsnygmhwvrqapgkglewvaviwyngsrtyy
gdsvkgrftisrdnskrtlymqmnslrtedtavyycardpdiltafsfdywgqgvlvtvs
sastkgpsvfplaptaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqssglyslss
vvtvpssslgtqtyicnvnhkpsntkvdkkvepks

Chain 'C':
Sequence, based on SEQRES records: (download)

>8fabC (C:)
syeltqppsvsvspgqtaritcsanalpnqyaywyqqkpgrapvmviykdtqrpsgipqr
fssstsgttvtltisgvqaedeadyycqawdnsasifgggtkltvlgqpkaapsvtlfpp
sseelqankatlvclisdfypgavtvawkadsspikagvetttpskqsnnkyaassylsl
tpeqwkshrsyscqvthegstvektvaptecs

Sequence, based on observed residues (ATOM records): (download)

>8fabC (C:)
eltqppsvsvspgqtaritcsanalpnqyaywyqqkpgrapvmviykdtqrpsgipqrfs
sstsgttvtltisgvqaedeadyycqawdnsasifgggtkltvlgqpkaapsvtlfppss
eelqankatlvclisdfypgavtvawkadsspikagvetttpskqsnnkyaassylsltp
eqwkshrsyscqvthegstvektvap

Chain 'D':
Sequence, based on SEQRES records: (download)

>8fabD (D:)
avklvqagggvvqpgrslrlsciasgftfsnygmhwvrqapgkglewvaviwyngsrtyy
gdsvkgrftisrdnskrtlymqmnslrtedtavyycardpdiltafsfdywgqgvlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepksc

Sequence, based on observed residues (ATOM records): (download)

>8fabD (D:)
avklvqagggvvqpgrslrlsciasgftfsnygmhwvrqapgkglewvaviwyngsrtyy
gdsvkgrftisrdnskrtlymqmnslrtedtavyycardpdiltafsfdywgqgvlvtvs
sastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlqs
sglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk